| Trial ID: | L7354 |
| Source ID: | NCT01483651
|
| Associated Drug: |
Glucagon
|
| Title: |
Physiologic Response to Glucagon at Varying Insulin Levels
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT01483651/results
|
| Conditions: |
Type 1 Diabetes Mellitus
|
| Interventions: |
DRUG: Glucagon|DRUG: Insulin
|
| Outcome Measures: |
Primary: Area Under the Curve for Glucose Above Baseline, The change in the rate of glucose appearance will be assessed by measuring the stable glucose isotope (dideuterated glucose, D2) using a gas chromatography-mass spectrometry assay. The units of the area under the curve are defined as milligrams per kilogram of glucose, since the dependent variable is a rate of glucose production \[mg/kg/min\] measured over time \[min\]. The time variable therefore cancels out. Additionally, this area under the curve is being normalized per microgram of glucagon delivered., 60 minutes after each glucagon administration |
|
| Sponsor/Collaborators: |
Sponsor: Legacy Health System | Collaborators: Juvenile Diabetes Research Foundation|Oregon Health and Science University
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
|
| Enrollment: |
11
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2011-11
|
| Completion Date: |
2013-03
|
| Results First Posted: |
2014-09-22
|
| Last Update Posted: |
2016-03-29
|
| Locations: |
Legacy Health System, Portland, Oregon, 97210, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT01483651
|
