| Trial ID: | L7367 |
| Source ID: | NCT03329651
|
| Associated Drug: |
Metformin Treatment
|
| Title: |
The Interaction Between Metformin and Acute Exercise
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Impaired Glucose Tolerance|Diabetes Mellitus, Type 2
|
| Interventions: |
DRUG: Metformin treatment|DRUG: Placebo treatment
|
| Outcome Measures: |
Primary: Difference in postprandial glycemic control as assessed by mean blood glucose concentration during a 4 hour mixed-meal tolerance test, Day 17 (no acute exercise [control day]) and 24 (following an acute exercise bout) | Secondary: Difference in endogenous glucose production as assessed by rate of infused glucose tracer appearance in blood, Day 17 (no acute exercise [control day]) and 24 (following an acute exercise bout)|Difference in exogenous glucose uptake as assessed by rate of ingested glucose tracer appearance in blood, Day 17 (no acute exercise [control day]) and 24 (following an acute exercise bout)|Difference in peripheral glucose uptake as assessed by rate of glucose disappearance from blood, Day 17 (no acute exercise [control day]) and 24 (following an acute exercise bout)
|
| Sponsor/Collaborators: |
Sponsor: Kristian Karstoft | Collaborators: University of Copenhagen
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
|
| Enrollment: |
34
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2017-11-10
|
| Completion Date: |
2018-10-01
|
| Results First Posted: |
|
| Last Update Posted: |
2018-11-09
|
| Locations: |
Center for aktiv sundhed, Copenhagen, Copenhagen N, 2200, Denmark
|
| URL: |
https://clinicaltrials.gov/show/NCT03329651
|
