| Outcome Measures: |
Primary: urinary tract infections rate, Urinary tract infections will be strictly monitored in all enrolled patients (both group A and group B). The rate of urinary tract infections in the first 24 months from the enrolment will be compared between 2 groups, during the first 24 months from enrolment | Secondary: febrile urinary tract infections, Febrile urinary tract infections will be strictly monitored in all enrolled patients (both group A and group B). The rate of febrile urinary tract infections in the first 24 months from the enrolment will be compared between 2 groups, during the first 24 months from enrolment|renal scars, the appearance of renal scars in a dimercaptosuccinic acid (DMSA) scan will be detected at 2 and 5 years from enrolment and compared between the 2 groups., at 2 years and 5 years from enrolment|serum creatinine (renal function), The renal function (serum creatinine) will be monitored for all enrolled patients to explore the appearance and progression of renal damage, at the enrolment,1 year, 2 years, 3 years, 4 years, 5 years|hypertension, the appearance of hypertension will be monitored at every visit in all enrolled children, at 4, 8, 12, 18, 24, 36, 48, 60 months from enrolment|proteinuria, the appearance of proteinuria will be monitored at every visit in all enrolled children, at 4, 8, 12, 18, 24, 36, 48, 60 months from enrolment|body mass index, body mass index will be evaluated at 2 and 5 years of follow-up and it will be correlated to the use of antibiotic prophylaxis, at 2 and 5 years from enrolment|serum cystatin C (renal function), The renal function (serum cystatin-C) will be monitored for all enrolled patients to explore the appearance and progression of renal damage, at the enrolment,1 year, 2 years, 3 years, 4 years, 5 years|modification in gut microbiota induced by continuous antibiotic exposure during the first months of life, A stool sample will be collected, frozen and stored for gut microbiota and resistome profile analysis, at the enrollment, 4 months, 8 months, 12 months, 2 years, 3 years, 4 years, 5 years
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