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Clinical Trial Details

Trial ID: L1305
Source ID: NCT01002872
Associated Drug: Lanthanum Carbonate (Fosrenol)
Title: The Effect of Lanthanum Carbonate on Fibroblast Growth Factor 23 ( FGF23) in Chronic Kidney Disease
Acronym:
Status: COMPLETED
Study Results: YES
Results: https://ClinicalTrials.gov/show/NCT01002872/results
Conditions: Metabolic Bone Disease
Interventions: DRUG: Lanthanum Carbonate (Fosrenol)|DRUG: placebo
Outcome Measures: Primary: Fibroblast Growth Factor (FGF) 23 Mean Change From Baseline, Mean change from baseline of FGF23 in subjects treated with Lanthanum Carbonate verse placebo at 60 days, Baseline, 60 days | Secondary: Calcium Mean Change From Baseline, Mean change from baseline Calcium level at 60 days, Baseline, 60 days|Serum Phosphate Mean Change From Baseline, Mean change from baseline serum phosphate at 60 days, Baseline, 60 days|Change From Baseline Serum Parathyroid Hormone, Change from baseline serum parathyroid hormone at 60 days, Baseline, 60 days|1,25 Dihydroxyvitamin D 3 Mean Change From Baseline, Mean change from baseline 1,25 dihydroxyvitamin D 3 at 60 days, Baseline, 60 days|25 Hydroxyvitamin D Mean Change From Baseline, Mean change from baseline 25 hydroxyvitamin D at 60 days, Baseline, 60 days|Serum Alkaline Phosphatase Mean Change From Baseline, Mean change from baseline serum alkaline phosphatase at 60 days, Baseline, 60 days|Serum Osteocalcin Mean Change From Baseline, Mean change from baseline serum osteocalcin at 60 days, Baseline, 60 days|24 Hour Urine Phosphate Mean Change From Baseline, Mean change from baseline 24 hour urine phosphate at 60 days, Baseline, 60 days
Sponsor/Collaborators: Sponsor: Endeavor Health | Collaborators: Shire
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases:
Enrollment: 19
Study Type: INTERVENTIONAL
Study Designs: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Start Date: 2009-10
Completion Date: 2012-12
Results First Posted: 2023-09-21
Last Update Posted: 2023-09-21
Locations: NorthShore University HealthSystem, Evanston, Illinois, 60201, United States
URL: https://clinicaltrials.gov/show/NCT01002872