Clinical Trial Details
| Trial ID: | L1464 |
| Source ID: | NCT01111422 |
| Associated Drug: | N-Acetylcysteine |
| Title: | Anti-Oxidant Effect on Peritoneal Membrane in Peritoneal Dialysis (PD) Patients |
| Acronym: | |
| Status: | UNKNOWN |
| Study Results: | NO |
| Results: | |
| Conditions: | End-Stage Kidney Disease|Peritoneal Dialysis |
| Interventions: | DRUG: N-acetylcysteine |
| Outcome Measures: | Primary: Peritoneal membrane function, Changes in peritoneal membrane function (Δ D/Pcreatinine, ΔD/Purea) with peritoneal equilibrium test, 6 months | Secondary: Oxydative stress status, Measurement of oxydative stress status with plasma and RBC (GSH/GSSG, 8-OHdG), 6 months|Mesothelial cell transformation (Epithelial to Mesenchymal Transition), Morphology was analysed with peritoneal dialysate isolated mesothelial cell, 6 month|Residual renal function, Changes in residual renal function (ΔKt/Vurea, ΔeGFR), 6 month|Peritoneal membrane function, Changes in peritoneal membrane function (Δ D/Pcreatinine, ΔD/Purea) with peritoneal equilibrium test, 2 months |
| Sponsor/Collaborators: | Sponsor: Ewha Womans University |
| Gender: | ALL |
| Age: | ADULT, OLDER_ADULT |
| Phases: | PHASE4 |
| Enrollment: | 66 |
| Study Type: | INTERVENTIONAL |
| Study Designs: | Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT |
| Start Date: | 2010-03 |
| Completion Date: | 2011-12 |
| Results First Posted: | |
| Last Update Posted: | 2010-04-27 |
| Locations: | Ewha Womans University Mokdong Hospital, Seoul, Korea, Republic of |
| URL: | https://clinicaltrials.gov/show/NCT01111422 |
