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Clinical Trial Details

Trial ID: L1489
Source ID: NCT01581996
Associated Drug: Lanthanum Carbonate
Title: Fosrenol and Phosphorus Balance - Lanthanum Carbonate
Acronym:
Status: COMPLETED
Study Results: NO
Results:
Conditions: Chronic Kidney Failure|End-stage Renal Disease|Disorders Associated With Peritoneal Dialysis
Interventions: DRUG: lanthanum carbonate
Outcome Measures: Primary: Fecal Phosphorus and Body Phosphorus Balance, Dose response relationship between lanthanum carbonate(Fosrenol) intake and fecal phosphorus excretion and body phosphorus balance. Specifically, the phosphorus content of feces, urine, expended dialysate, diet and any vomitus or rejected food will be measured., Two years | Secondary: Fecal Calcium and Nitrogen and Body Calcium and Nitrogen Balance, Fecal calcium and nitrogen and calcium and nitrogen balance in chronic peritoneal dialysis patients eating lanthanum carbonate (Fosrenol) intake. Effect of ingestion of Fosrenol on serum phosphorus and hormonal regulators of phosphorus metabolism as serum, parathyroid hormone (PTH), fibroblast growth factor-23, 25-hydroxycholecalciferol (25(OH)D3), 1,25-dihydroxycholecalciferol (1,25(OH)2D3) and fetuin-A., Two years|Protein-nitrogen balance, Lanthanum carbonate (Fosrenol) and increased intestinal phosphate binding on protein-nitrogen balance., Two years|Gastrointestinal symptoms, Gastrointestinal symptoms, particularly for anorexia, nausea vomiting, abdominal pain, distention, flatulence, constipation, diarrhea., Two years
Sponsor/Collaborators: Sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases:
Enrollment: 9
Study Type: INTERVENTIONAL
Study Designs: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Start Date: 2012-03
Completion Date: 2017-05
Results First Posted:
Last Update Posted: 2017-05-09
Locations: Harbor-UCLA Medical Center, Torrance, California, 90509, United States
URL: https://clinicaltrials.gov/show/NCT01581996