| Trial ID: | L0169 |
| Source ID: | NCT01768637
|
| Associated Drug: |
Aspirin
|
| Title: |
Whole Blood Platelet Aggregation in Chronic Kidney Disease Patients on Aspirin Study
|
| Acronym: |
WiCKDonASA
|
| Status: |
COMPLETED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT01768637/results
|
| Conditions: |
Chronic Kidney Disease
|
| Interventions: |
DRUG: Aspirin|DRUG: Clopidogrel
|
| Outcome Measures: |
Primary: Whole Blood Platelet Aggregation to 0.5 Millimoles Arachidonic Acid, Citrated whole blood was used to measure platelet aggregation induced by agonist (arachidonic acid at 5 mM concentration) using impedance whole blood platelet aggregometry via a Chrono-log aggregometer. Values at baseline (visit 1) was compared between groups with post treatment values (visit 2) after 2 weeks of aspirin treatment, 2 weeks | Secondary: Whole Blood Platelet Aggregation to 2 µg/mL Collagen, Citrated whole blood was used to measure platelet aggregation induced by agonist (collagen at 2mM concentration) using impedance whole blood platelet aggregometry via a Chrono-log aggregometer. Values at baseline (visit 1) was compared between groups with post treatment values (visit 2) after 2 weeks of aspirin treatment, 2 weeks|Whole Blood Platelet Aggregation to 20 µg/mL Adenosine Diphosphate, Citrated whole blood was used to measure platelet aggregation induced by agonist (adenosine diphosphate at 20mM concentration) using impedance whole blood platelet aggregometry via a Chrono-log aggregometer. Values at baseline (visit 1) and on aspirin (visit 2) was compared between groups with post treatment values (visit 3) after 2 weeks of aspirin and clopidogrel treatment, 4 weeks
|
| Sponsor/Collaborators: |
Sponsor: University of Texas Southwestern Medical Center | Collaborators: American Heart Association
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE1
|
| Enrollment: |
48
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2013-01
|
| Completion Date: |
2014-06
|
| Results First Posted: |
2019-04-19
|
| Last Update Posted: |
2019-04-19
|
| Locations: |
University of Texas Southwestern Medical Center, Dallas, Texas, 75390-8856, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT01768637
|
