| Trial ID: | L0170 |
| Source ID: | NCT01341678
|
| Associated Drug: |
Lanthanum Carbonate
|
| Title: |
Circadian Rhythm Modulation by Dietary Phosphorus in Chronic Kidney Disease
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Chronic Kidney Disease
|
| Interventions: |
DRUG: Lanthanum Carbonate|DIETARY_SUPPLEMENT: NeutraPhos|OTHER: Diet Only
|
| Outcome Measures: |
Primary: Circadian rhythm of serum phosphorus, After 1 week of a controlled phosphorus diet patients will be hospitalized for 24 hours and serum phosphorus will be obtained every 4 hours. After a 4 day washout, each subject will cross over to a low phosphorus diet (for 1 week) followed by a 4 day washout and cross over to a high phosphorus diet for 1 week. At the end of each weekly diet a 24 hour hospitalization will occur with samples collected every 4 hours., 24 hour|Circadian rhythm of plasma fibroblast growth factor 23 (FGF23), After 1 week of a controlled phosphorus diet patients will be hospitalized for 24 hours and FGF23 will be obtained every 4 hours. After a 4 day washout, each subject will cross over to a low phosphorus diet (for 1 week) followed by a 4 day washout and cross over to a high phosphorus diet for 1 week. At the end of each weekly diet a 24 hour hospitalization will occur with samples collected every 4 hours., 24 hours|Circadian rhythm of salivary phosphorus, After 1 week of a controlled phosphorus diet patients will be hospitalized for 24 hours and salivary phosphorus will be obtained every 4 hours. After a 4 day washout, each subject will cross over to a low phosphorus diet (for 1 week) followed by a 4 day washout and cross over to a high phosphorus diet for 1 week. At the end of each weekly diet a 24 hour hospitalization will occur with samples collected every 4 hours., 24 hours |
|
| Sponsor/Collaborators: |
Sponsor: Geoffrey Block
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
|
| Enrollment: |
15
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
|
| Start Date: |
2011-04
|
| Completion Date: |
2011-10
|
| Results First Posted: |
|
| Last Update Posted: |
2014-02-11
|
| Locations: |
Denver Nephrologists, PC, Denver, Colorado, 80230, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT01341678
|
