| Outcome Measures: |
Primary: The amount of total use of midazolam and remifentanil drug consumptions in milligrams during operation time period., The comparison of total use of midazolam and remifentanil drug consumptions in milligrams during operation time period between the two groups., Through the operative time period up to two hours of time.|The evaluation of satisfaction of patient and surgeon by a questionnaire at the end of operation., The evaluation and comparison of satisfaction of patient and surgeon at the end of operation by a questionnaire between the two groups. Patient satisfaction level depending on the experience in general was evaluated at discharge from 0 to 4 point numerical scale: 0 = extremely dissatisfied; 1 = dissatisfied; 2 = neither satisfied nor dissatisfied; 3 = satisfied; 4 = extremely satisfied. Surgeon satisfaction level depending on the experience in general was evaluated at discharge from five point numerical scale: 0 = extremely poor; 1 = poor; 2 = fair; 3 = good; 4 = excellent., The collection of questionnaire at the end of operation in recovery room after recovery from sedation in a total of ten minutes time.|Modified Observer's Assessment of Alertness/Sedation Scale (MOSS/A) Scale, The comparison of level of sedation using MOSS/A scale that ranges from 0 to 6, with a score of 6 defined as awake or minimally sedated, and a score of 0 defined as general anesthesia every 10 to 15 minutes between the two groups., Through the operative time period up to two hours of time.|Modified Observer's Assessment of Alertness/Sedation Scale (MOSS/A) Scale, Repeated measure analysis of level of sedation by the use of the collected MOSS/A scale that ranges from 0 to 6, with a score of 6 defined as awake or minimally sedated, and a score of 0 defined as general anesthesia every 10 to 15 minutes within groups., Through the operative time period up to two hours of time.|Verbal Numerical Rating Scale, The comparison of level of pain using Verbal Numerical Rating Scale (VNRS; 0= no pain, 10=the worst possible pain imaginable) scale every 10 to 15 minutes between the two groups., Through the operative time period up to two hours of time.|Verbal Numerical Rating Scale, Repeated measure analysis of level of sedation by the use of the collected Verbal Numerical Rating Scale (VNRS; 0= no pain, 10=the worst possible pain imaginable) scale every 10 to 15 minutes between the two groups., Through the operative time period up to two hours of time.|Recovery time, The comparison of recovery time duration presented in minutes unit of time between the two groups., Through the recovery room time period before discharge up to one hour time.|Hospital stay, The comparison of hospital stay duration presented in hours unit of time between the two groups., Through the duration of stay in hospital before discharge up to seventy two hours time.|Systolic blood pressure values during operation and in the recovery room., The comparison of systolic blood pressure in mmHg unit values every 15 minutes between the two groups., Through the operative time period up to two hours of time and through the recovery room time period before discharge up to one hour time.|Heart rate values during operation and in the recovery room., The comparison of heart rate values in beats per minute unit every fifteen minutes between the two groups., Through the operative time period up to two hours of time and through the recovery room time period before discharge up to one hour time.|Pulse oximetry values during operation and in the recovery room., The comparison of pulse oximetry values in percent unit every fifteen minutes between the two groups., Through the operative time period up to two hours of time and through the recovery room time period before discharge up to one hour time.|Adverse events during operation and in the recovery room., Number of Participants With Adverse Events as Assessed by CTCAE Version 4.03., Through the operative time period up to two hours of time and through the recovery room time period before discharge up to one hour time. |
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