| Trial ID: | L1908 |
| Source ID: | NCT01597531
|
| Associated Drug: |
Liraglutide
|
| Title: |
Combinatorial Therapy for Peristent Type 2 Diabetes After Gastric Banding
|
| Acronym: |
|
| Status: |
TERMINATED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes|Gastric Banding
|
| Interventions: |
DRUG: Liraglutide|DRUG: Orlistat|DRUG: Liraglutide + Orlistat
|
| Outcome Measures: |
Primary: Type 2 diabetes remission, Hemoglobin a1c will be used to assess type 2 diabetes remission., baseline, 1 and 4 months post-randomization | Secondary: Whole body insulin sensitivity, Minimal model testing will be used to assess whole body insulin sensitivity., baseline, 1 and 4 months post-randomization|GLP-1 response, A mixed meal challenge will be used to assess meal-stimulated GLP-1 response., Baseline, 1 and 4 months post-randomization|First Phase Insulin secretion, Minimal model testing will be used to assess first phase insulin secretion., Baseline, 1 and 4 months post-randomization
|
| Sponsor/Collaborators: |
Sponsor: East Carolina University
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
1
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2012-06
|
| Completion Date: |
2014-06
|
| Results First Posted: |
|
| Last Update Posted: |
2018-02-05
|
| Locations: |
Brody School of Medicine at East Carolina University, Greenville, North Carolina, 28590, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT01597531
|
