Logo 1 Logo 2

Clinical Trial Details

Trial ID: L2179
Source ID: NCT00839527
Associated Drug: Placebo To Match Albiglutide
Title: A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes
Acronym:
Status: COMPLETED
Study Results: YES
Results: https://ClinicalTrials.gov/show/NCT00839527/results
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: placebo to match albiglutide|BIOLOGICAL: albiglutide|DRUG: metformin|DRUG: glimepiride|DRUG: pioglitazone|DRUG: placebo to match pioglitazone
Outcome Measures: Primary: Change From Baseline (BL) in Glycosylated Hemoglobin (HbA1c) at Week 52, HbA1c is a form of hemoglobin that is measured primarily to identify the average plasma glucose concentration over a 2- to 3-month period. The BL HbA1c value is defined as the last non-missing value before the start of treatment. Change from BL was calculated as the value at Week 52 minus the value at BL. Based on analysis of covariance (ANCOVA): change = treatment + BL HbA1c + prior myocardial infarction history + age category + region. The last observation carried forward (LOCF) method was used to impute missing post-BL HbA1c values; the last non-missing post-BL on-treatment measurement was used to impute the missing measurement. HbA1c values obtained after hyperglycemic rescue were treated as missing and were replaced with pre-rescue values. Nine par. with post-BL values obtained \>14 days after the last dose or after hyperglycemic rescue were included in the analysis population but were not analyzed for this endpoint., Baseline and Week 52 | Secondary: Change From Baseline in HbA1c at Week 104 and Week 156, HbA1c is a form of hemoglobin that is measured primarily to identify the average plasma glucose concentration over a 2- to 3-month period. The Baseline HbA1c value is defined as the last non-missing value before the start of treatment. Change from Baseline was calculated as the post-Baseline value minus the Baseline value. This analysis used observed HbA1c values, excluding those obtained after hyperglycemia rescue; no missing data imputation was performed., Baseline, Week 104, and Week 156|Change From Baseline in Fasting Plasma Glucose (FPG) at Week 52, The FPG test measures blood sugar levels after the participant has not eaten (fasted) for 12 to 14 hours. The Baseline FPG value is the last non-missing value before the start of treatment. The LOCF method was used to impute missing post-Baseline FPG values. FPG values obtained after hyperglycemia rescue were treated as missing and replaced with pre-rescue values. Change from Baseline was calculated as the post-Baseline value minus the Baseline value. Based on ANCOVA: change = treatment + Baseline FPG + Baseline HbA1c category + prior myocardial infarction history + age category + region., Baseline and Week 52|Change From Baseline in FPG at Week 104 and Week 156, The FPG test measures blood sugar levels after the participant has not eaten (fasted) for 12 to 14 hours. The Baseline FPG value is the last non-missing value before the start of treatment. Change from Baseline was calculated as the post-Baseline value minus the Baseline value. This analysis used observed FPG values excluding those obtained after hyperglycemia rescue; no missing data imputation was performed., Baseline, Week 104, and Week 156|Time to Hyperglycemia Rescue, Participants who experienced persistent hyperglycemia (high blood glucose) could have qualified for hyperglycemia rescue. The conditions for hyperglycemia rescue were as follows: FPG \>=280 milligrams/deciliter (mg/dL) between \>=Week 2 and \<Week 4; FPG \>=250 mg/dL between \>=Week 4 and \<Week 12; HbA1c \>=8.5% and a \<=0.5% reduction from Baseline between \>=Week 12 and \<Week 24; HbA1c \>=8.5% between \>=Week 24 and \<Week 48; HbA1c \>=8.0% between \>= Week 48 and \<Week 156. Participants could have been rescued at any time on or after Week 2. Time to hyperglycemia rescue is defined as the time between the date of the first dose of study medication and the date of hyperglycemia rescue plus 1 day, or the time between the date of the first dose of study medication and the date of the last visit during the active treatment period plus 1 day for participants not requiring rescue. This time was divided by 7 to express the result in weeks., From the start of study medication until the end of the treatment (up to Week 156)|Number of Participants Who Achieved Clinically Meaningful HbA1c Response Levels of <6.5%, <7%, and <7.5% at Week 52, The number of participants who acheieved the HbA1c treatment goal (i.e., HbA1c response levels of \<6.5%, \<7%, and \<7.5% at Week 52) was assessed. Values were carried forward for participants who were rescued or discontinued from active treatment before Week 52., Week 52|Number of Participants Who Achieved Clinically Meaningful HbA1c Response Levels of <6.5%, <7%, and <7.5% at Week 156, The number of participants who acheieved the HbA1c treatment goal (i.e., HbA1c response levels of \<6.5%, \<7%, and \<7.5% at Week 156) was assessed., Week 156|Change From Baseline in Body Weight at Week 52, The Baseline value is the last non-missing value before the start of treatment. Change from Baseline was calculated as the post-Baseline weight minus the Baseline weight. The LOCF method was used to impute missing post-Baseline weight values. Weight values obtained after hyperglycemia rescue were treated as missing and replaced with pre-rescue values. Based on ANCOVA: change = treatment + Baseline weight + Baseline HbA1c category + prior myocardial infarction history + age category + region., Baseline and Week 52|Change From Baseline in Body Weight at Week 104 and Week 156, The Baseline value is the last non-missing value before the start of treatment. Change from Baseline was calculated as the post-Baseline weight minus the Baseline weight. This analysis used observed body weight values excluding those obtained after hyperglycemia rescue; no missing data imputation was performed., Baseline, Week 104, and Week 156
Sponsor/Collaborators: Sponsor: GlaxoSmithKline
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases: PHASE3
Enrollment: 685
Study Type: INTERVENTIONAL
Study Designs: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Start Date: 2009-02
Completion Date: 2013-04
Results First Posted: 2014-07-01
Last Update Posted: 2017-01-09
Locations: GSK Investigational Site, Alabaster, Alabama, 35007, United States|GSK Investigational Site, Birmingham, Alabama, 35205, United States|GSK Investigational Site, Birmingham, Alabama, 35235, United States|GSK Investigational Site, Birmingham, Alabama, 35242, United States|GSK Investigational Site, Dothan, Alabama, 36301, United States|GSK Investigational Site, Mobile, Alabama, 36617, United States|GSK Investigational Site, Tuscaloosa, Alabama, 35406, United States|GSK Investigational Site, Chandler, Arizona, 85225, United States|GSK Investigational Site, Gilbert, Arizona, 85295, United States|GSK Investigational Site, Green Valley, Arizona, 85614, United States|GSK Investigational Site, Phoenix, Arizona, 85023, United States|GSK Investigational Site, Phoenix, Arizona, 85028, United States|GSK Investigational Site, Phoenix, Arizona, 85032, United States|GSK Investigational Site, Phoenix, Arizona, 85050, United States|GSK Investigational Site, Phoenix, Arizona, 85051, United States|GSK Investigational Site, Tucson, Arizona, 85712, United States|GSK Investigational Site, Tucson, Arizona, 85745, United States|GSK Investigational Site, Bull Shoals, Arkansas, 72619, United States|GSK Investigational Site, Harrisburg, Arkansas, 72432, United States|GSK Investigational Site, Hot Springs, Arkansas, 71913, United States|GSK Investigational Site, Jonesboro, Arkansas, 72401, United States|GSK Investigational Site, Searcy, Arkansas, 72143, United States|GSK Investigational Site, Buena Park, California, 90620, United States|GSK Investigational Site, Chino, California, 91710, United States|GSK Investigational Site, Chula Vista, California, 91910, United States|GSK Investigational Site, Commerce, California, 90040, United States|GSK Investigational Site, Escondido, California, 92026, United States|GSK Investigational Site, Foothill Ranch, California, 92610, United States|GSK Investigational Site, Fountain Valley, California, 92708, United States|GSK Investigational Site, Fresno, California, 93720, United States|GSK Investigational Site, Fullerton, California, 92835, United States|GSK Investigational Site, Huntington Beach, California, 92646, United States|GSK Investigational Site, Indio, California, 92201, United States|GSK Investigational Site, La Jolla, California, 92037, United States|GSK Investigational Site, Lakewood, California, 90712, United States|GSK Investigational Site, Loma Linda, California, 92354, United States|GSK Investigational Site, Long Beach, California, 90806, United States|GSK Investigational Site, Los Alamitos, California, 90720, United States|GSK Investigational Site, Los Angeles, California, 90017, United States|GSK Investigational Site, Los Angeles, California, 90022, United States|GSK Investigational Site, Los Angeles, California, 90025, United States|GSK Investigational Site, Mission Viejo, California, 92691, United States|GSK Investigational Site, Northridge, California, 91325, United States|GSK Investigational Site, Palm Desert, California, 92260, United States|GSK Investigational Site, Palm Springs, California, 92262, United States|GSK Investigational Site, Pasadena, California, 91105, United States|GSK Investigational Site, Riverside, California, 92506, United States|GSK Investigational Site, Sacramento, California, 95825, United States|GSK Investigational Site, Sacramento, California, 95831, United States|GSK Investigational Site, San Diego, California, 92117, United States|GSK Investigational Site, San Diego, California, 92120, United States|GSK Investigational Site, Santa Ana, California, 92701, United States|GSK Investigational Site, Satna Monica, California, 90404, United States|GSK Investigational Site, Spring Valley, California, 91978, United States|GSK Investigational Site, Tarzana, California, 91356, United States|GSK Investigational Site, Tustin, California, 92780, United States|GSK Investigational Site, Victorville, California, 92395, United States|GSK Investigational Site, Walnut Creek, California, 94598, United States|GSK Investigational Site, West Hills, California, 91307, United States|GSK Investigational Site, Arvada, Colorado, 80005, United States|GSK Investigational Site, Denver, Colorado, 80209, United States|GSK Investigational Site, New Britain, Connecticut, 06050, United States|GSK Investigational Site, Trumbull, Connecticut, 06611, United States|GSK Investigational Site, Waterbury, Connecticut, 06708, United States|GSK Investigational Site, Middletown, Delaware, 19709, United States|GSK Investigational Site, Boynton Beach, Florida, 33426, United States|GSK Investigational Site, Boynton Beach, Florida, 33437, United States|GSK Investigational Site, Clearwater, Florida, 33756, United States|GSK Investigational Site, Clearwater, Florida, 33765, United States|GSK Investigational Site, Cocoa, Florida, 32927, United States|GSK Investigational Site, Cutler Bay, Florida, 33189, United States|GSK Investigational Site, Deerfield Beach, Florida, 33442, United States|GSK Investigational Site, Delray Beach, Florida, 33445, United States|GSK Investigational Site, Edgewater, Florida, 32132, United States|GSK Investigational Site, Fort Lauderdale, Florida, 33316, United States|GSK Investigational Site, Gainesville, Florida, 32605, United States|GSK Investigational Site, Hallandale Beach, Florida, 33009, United States|GSK Investigational Site, Hialeah, Florida, 33012, United States|GSK Investigational Site, Hialeah, Florida, 33013, United States|GSK Investigational Site, Hollywood, Florida, 33023, United States|GSK Investigational Site, Lauderdale Lakes, Florida, 33319, United States|GSK Investigational Site, Marianna, Florida, 32446, United States|GSK Investigational Site, Miami, Florida, 33135, United States|GSK Investigational Site, Miami, Florida, 33156, United States|GSK Investigational Site, North Miami, Florida, 33161, United States|GSK Investigational Site, Ocala, Florida, 34471, United States|GSK Investigational Site, Orlando, Florida, 32822, United States|GSK Investigational Site, Ormond Beach, Florida, 32174, United States|GSK Investigational Site, Oviedo, Florida, 32765, United States|GSK Investigational Site, Panama City, Florida, 32401, United States|GSK Investigational Site, Pembroke Pines, Florida, 33026, United States|GSK Investigational Site, Pembroke Pines, Florida, 33027, United States|GSK Investigational Site, Plantation, Florida, 33317, United States|GSK Investigational Site, Ponte Verda, Florida, 32081, United States|GSK Investigational Site, St. Cloud, Florida, 34769, United States|GSK Investigational Site, St. Petersburg, Florida, 33709, United States|GSK Investigational Site, Tampa, Florida, 33603, United States|GSK Investigational Site, West Palm Beach, Florida, 33401, United States|GSK Investigational Site, Atlanta, Georgia, 30308, United States|GSK Investigational Site, Atlanta, Georgia, 30312, United States|GSK Investigational Site, Atlanta, Georgia, 30328, United States|GSK Investigational Site, Atlanta, Georgia, 30338, United States|GSK Investigational Site, Atlanta, Georgia, 30342, United States|GSK Investigational Site, Blue Ridge, Georgia, 30513, United States|GSK Investigational Site, Columbus, Georgia, 31904, United States|GSK Investigational Site, Decatur, Georgia, 30032, United States|GSK Investigational Site, Savannah, Georgia, 31406, United States|GSK Investigational Site, Savannah, Georgia, 31419, United States|GSK Investigational Site, Snellville, Georgia, 30078, United States|GSK Investigational Site, Stone Mountain, Georgia, 30088, United States|GSK Investigational Site, Tucker, Georgia, 30084, United States|GSK Investigational Site, Honolulu, Hawaii, 96813, United States|GSK Investigational Site, Honolulu, Hawaii, 96814, United States|GSK Investigational Site, Boise, Idaho, 83702, United States|GSK Investigational Site, Idaho Falls, Idaho, 83404, United States|GSK Investigational Site, Aurora, Illinois, 60504, United States|GSK Investigational Site, Chicago, Illinois, 60607, United States|GSK Investigational Site, Evergreen Park, Illinois, 60805, United States|GSK Investigational Site, Gurnee, Illinois, 60031, United States|GSK Investigational Site, La Grange, Illinois, 60525, United States|GSK Investigational Site, Naperville, Illinois, 60564, United States|GSK Investigational Site, Peoria, Illinois, 61602, United States|GSK Investigational Site, Avon, Indiana, 46123, United States|GSK Investigational Site, Evansville, Indiana, 47714, United States|GSK Investigational Site, Fishers, Indiana, 46037, United States|GSK Investigational Site, La Porte, Indiana, 46350, United States|GSK Investigational Site, Lafayette, Indiana, 47904, United States|GSK Investigational Site, South Bend, Indiana, 46614, United States|GSK Investigational Site, Council Bluffs, Iowa, 51501, United States|GSK Investigational Site, Des Moines, Iowa, 50314, United States|GSK Investigational Site, Dubuque, Iowa, 52001, United States|GSK Investigational Site, Iowa City, Iowa, 52243, United States|GSK Investigational Site, Waterloo, Iowa, 50701, United States|GSK Investigational Site, Arkansas City, Kansas, 67005, United States|GSK Investigational Site, Mission, Kansas, 66202, United States|GSK Investigational Site, Newton, Kansas, 67114, United States|GSK Investigational Site, Overland Park, Kansas, 66211, United States|GSK Investigational Site, Topeka, Kansas, 66606, United States|GSK Investigational Site, Fort Mitchell, Kentucky, 41017, United States|GSK Investigational Site, Lexington, Kentucky, 40503, United States|GSK Investigational Site, Lexington, Kentucky, 40504, United States|GSK Investigational Site, Madisonville, Kentucky, 42431, United States|GSK Investigational Site, Paducah, Kentucky, 42003, United States|GSK Investigational Site, Covington, Louisiana, 70433, United States|GSK Investigational Site, Lake Charles, Louisiana, 70601, United States|GSK Investigational Site, Shreveport, Louisiana, 71101, United States|GSK Investigational Site, Shreveport, Louisiana, 71115, United States|GSK Investigational Site, Baltimore, Maryland, 21237-3998, United States|GSK Investigational Site, Hyattsville, Maryland, 20782, United States|GSK Investigational Site, Oxon Hill, Maryland, 20745, United States|GSK Investigational Site, Haverhill, Massachusetts, 01830, United States|GSK Investigational Site, Bay City, Michigan, 48706, United States|GSK Investigational Site, Benzonia, Michigan, 49616, United States|GSK Investigational Site, Bloomfield Hills, Michigan, 48302, United States|GSK Investigational Site, Cadillac, Michigan, 49601, United States|GSK Investigational Site, Dearborn, Michigan, 48124, United States|GSK Investigational Site, Kalamazoo, Michigan, 49009, United States|GSK Investigational Site, Kalamazoo, Michigan, 49048, United States|GSK Investigational Site, St Clair Shores, Michigan, 48081, United States|GSK Investigational Site, Minneapolis, Minnesota, 55430, United States|GSK Investigational Site, Gulfport, Mississippi, 39501, United States|GSK Investigational Site, Picayune, Mississippi, 39466, United States|GSK Investigational Site, Rolling Fork, Mississippi, 39159, United States|GSK Investigational Site, Chesterfield, Missouri, 63017, United States|GSK Investigational Site, Jefferson City, Missouri, 65109, United States|GSK Investigational Site, Kansas City, Missouri, 64106, United States|GSK Investigational Site, Kansas City, Missouri, United States|GSK Investigational Site, Springfield, Missouri, 65807, United States|GSK Investigational Site, St. Louis, Missouri, 63117, United States|GSK Investigational Site, St. Louis, Missouri, 63141, United States|GSK Investigational Site, West Plains, Missouri, 65775, United States|GSK Investigational Site, Billings, Montana, 59102, United States|GSK Investigational Site, Butte, Montana, 59701, United States|GSK Investigational Site, Great Falls, Montana, 59405, United States|GSK Investigational Site, Broken Bow, Nebraska, 68822, United States|GSK Investigational Site, Lincoln, Nebraska, 68516, United States|GSK Investigational Site, Omaha, Nebraska, 68124, United States|GSK Investigational Site, Omaha, Nebraska, 68131, United States|GSK Investigational Site, Omaha, Nebraska, 68134, United States|GSK Investigational Site, Las Vegas, Nevada, 89102, United States|GSK Investigational Site, Las Vegas, Nevada, 89104, United States|GSK Investigational Site, Las Vegas, Nevada, 89106, United States|GSK Investigational Site, Las Vegas, Nevada, 89128, United States|GSK Investigational Site, Las Vegas, Nevada, 89130, United States|GSK Investigational Site, Berlin, New Jersey, 08009, United States|GSK Investigational Site, Elizabeth, New Jersey, 07202, United States|GSK Investigational Site, Haddon Heights, New Jersey, 08035, United States|GSK Investigational Site, Hainesport, New Jersey, 08036, United States|GSK Investigational Site, New Brunswick, New Jersey, 08903, United States|GSK Investigational Site, Stratford, New Jersey, 08084, United States|GSK Investigational Site, Albuquerque, New Mexico, 87106, United States|GSK Investigational Site, New York, New York, 10022, United States|GSK Investigational Site, New York, New York, 10025, United States|GSK Investigational Site, North Massapequa, New York, 11758, United States|GSK Investigational Site, Asheboro, North Carolina, 27203, United States|GSK Investigational Site, Asheville, North Carolina, 28803, United States|GSK Investigational Site, Burlington, North Carolina, 27215, United States|GSK Investigational Site, Calabash, North Carolina, 28467, United States|GSK Investigational Site, Durham, North Carolina, 27710, United States|GSK Investigational Site, Fayetteville, North Carolina, 28304, United States|GSK Investigational Site, Greensboro, North Carolina, 27405, United States|GSK Investigational Site, Hickory, North Carolina, 28601, United States|GSK Investigational Site, Huntersville, North Carolina, 28078, United States|GSK Investigational Site, Lenoir, North Carolina, 28645, United States|GSK Investigational Site, Mint HIll, North Carolina, 28227, United States|GSK Investigational Site, Morehead City, North Carolina, 28557, United States|GSK Investigational Site, Shelby, North Carolina, 28150, United States|GSK Investigational Site, Tabor City, North Carolina, 28463, United States|GSK Investigational Site, Akron, Ohio, 44320, United States|GSK Investigational Site, Canal Fulton, Ohio, 44614, United States|GSK Investigational Site, Cincinnati, Ohio, 45211, United States|GSK Investigational Site, Cincinnati, Ohio, 45219, United States|GSK Investigational Site, Cincinnati, Ohio, 45227, United States|GSK Investigational Site, Cincinnati, Ohio, 45245, United States|GSK Investigational Site, Cleveland, Ohio, 44122, United States|GSK Investigational Site, Columbus, Ohio, 43212, United States|GSK Investigational Site, Columbus, Ohio, 43213, United States|GSK Investigational Site, Dayton, Ohio, 45432, United States|GSK Investigational Site, Dayton, Ohio, 45439, United States|GSK Investigational Site, Kettering, Ohio, 45429, United States|GSK Investigational Site, Mason, Ohio, 45040, United States|GSK Investigational Site, Maumee, Ohio, 43537-9402, United States|GSK Investigational Site, Thornville, Ohio, 43076, United States|GSK Investigational Site, Zanesville, Ohio, 43701, United States|GSK Investigational Site, Oklahoma City, Oklahoma, 73103, United States|GSK Investigational Site, Tulsa, Oklahoma, 74104, United States|GSK Investigational Site, Tulsa, Oklahoma, 74136, United States|GSK Investigational Site, Ashland, Oregon, 97520, United States|GSK Investigational Site, Bensalem, Pennsylvania, 19020, United States|GSK Investigational Site, Carlisle, Pennsylvania, 17013, United States|GSK Investigational Site, Downington, Pennsylvania, 19335, United States|GSK Investigational Site, Harrisburg, Pennsylvania, 17112, United States|GSK Investigational Site, Landsdale, Pennsylvania, 19446, United States|GSK Investigational Site, Melrose Park, Pennsylvania, 19027, United States|GSK Investigational Site, Tipton, Pennsylvania, 16684, United States|GSK Investigational Site, Uniontown, Pennsylvania, 15401, United States|GSK Investigational Site, Cumberland, Rhode Island, 02864, United States|GSK Investigational Site, East Providence, Rhode Island, 02914, United States|GSK Investigational Site, Columbia, South Carolina, 29201, United States|GSK Investigational Site, Greenville, South Carolina, 29601, United States|GSK Investigational Site, Greenville, South Carolina, 29615, United States|GSK Investigational Site, Greer, South Carolina, 29651, United States|GSK Investigational Site, Manning, South Carolina, 29102, United States|GSK Investigational Site, Murrells Inlet, South Carolina, 29576, United States|GSK Investigational Site, North Myrtle Beach, South Carolina, 29582, United States|GSK Investigational Site, Orangeburg, South Carolina, 29115, United States|GSK Investigational Site, Simpsonville, South Carolina, 29681, United States|GSK Investigational Site, Taylors, South Carolina, 29687, United States|GSK Investigational Site, Bristol, Tennessee, 37620, United States|GSK Investigational Site, Chattanooga, Tennessee, 37421, United States|GSK Investigational Site, Clarksville, Tennessee, 37043, United States|GSK Investigational Site, Columbia, Tennessee, 38401, United States|GSK Investigational Site, Fayetteville, Tennessee, 37334, United States|GSK Investigational Site, Germantown, Tennessee, 38138, United States|GSK Investigational Site, Johnson City, Tennessee, 37604, United States|GSK Investigational Site, McKenzie, Tennessee, 38201, United States|GSK Investigational Site, Memphis, Tennessee, 38125, United States|GSK Investigational Site, Nashville, Tennessee, 37203, United States|GSK Investigational Site, Tullahoma, Tennessee, 37398, United States|GSK Investigational Site, Arlington, Texas, 76012, United States|GSK Investigational Site, Bedford, Texas, 76201, United States|GSK Investigational Site, Cleburne, Texas, 76033, United States|GSK Investigational Site, Corpus Christi, Texas, 78404, United States|GSK Investigational Site, Corpus Christi, Texas, 78414, United States|GSK Investigational Site, Dallas, Texas, 75224, United States|GSK Investigational Site, Dallas, Texas, 75230, United States|GSK Investigational Site, Dallas, Texas, 75235, United States|GSK Investigational Site, Dallas, Texas, 75246, United States|GSK Investigational Site, Dallas, Texas, 75251, United States|GSK Investigational Site, Deer Park, Texas, 77536, United States|GSK Investigational Site, El Paso, Texas, 79925, United States|GSK Investigational Site, Fort Worth, Texas, 76104, United States|GSK Investigational Site, Fort Worth, Texas, 76135, United States|GSK Investigational Site, Houston, Texas, 77024, United States|GSK Investigational Site, Houston, Texas, 77030, United States|GSK Investigational Site, Houston, Texas, 77034, United States|GSK Investigational Site, Houston, Texas, 77036, United States|GSK Investigational Site, Houston, Texas, 77055, United States|GSK Investigational Site, Houston, Texas, 77058, United States|GSK Investigational Site, Houston, Texas, 77070, United States|GSK Investigational Site, Houston, Texas, 77074, United States|GSK Investigational Site, Hurst, Texas, 76054, United States|GSK Investigational Site, Katy, Texas, 77450, United States|GSK Investigational Site, Lake Jackson, Texas, 77566, United States|GSK Investigational Site, Lewisville, Texas, 75067, United States|GSK Investigational Site, Midland, Texas, 79707, United States|GSK Investigational Site, North Richland Hills, Texas, 76180, United States|GSK Investigational Site, Odessa, Texas, 79761, United States|GSK Investigational Site, San Antonio, Texas, 78215, United States|GSK Investigational Site, San Antonio, Texas, 78217, United States|GSK Investigational Site, San Antonio, Texas, 78218, United States|GSK Investigational Site, San Antonio, Texas, 78224, United States|GSK Investigational Site, San Antonio, Texas, 78229, United States|GSK Investigational Site, San Antonio, Texas, 78258, United States|GSK Investigational Site, Schertz, Texas, 78154, United States|GSK Investigational Site, Sugar Land, Texas, 77479, United States|GSK Investigational Site, Sugarland, Texas, 77479, United States|GSK Investigational Site, Temple, Texas, 76508, United States|GSK Investigational Site, Orem, Utah, 84058, United States|GSK Investigational Site, Salt Lake City, Utah, 84102, United States|GSK Investigational Site, Salt Lake City, Utah, 84107, United States|GSK Investigational Site, West Jordan, Utah, 84088, United States|GSK Investigational Site, West Valley City, Utah, 84120, United States|GSK Investigational Site, South Burlington, Vermont, 05403, United States|GSK Investigational Site, Burke, Virginia, 22015, United States|GSK Investigational Site, Hampton, Virginia, 23666, United States|GSK Investigational Site, Manassas, Virginia, 20110, United States|GSK Investigational Site, Norfolk, Virginia, 23502, United States|GSK Investigational Site, Richmond, Virginia, 23294, United States|GSK Investigational Site, Suffolk, Virginia, United States|GSK Investigational Site, Virgina Beach, Virginia, 23455, United States|GSK Investigational Site, Weber City, Virginia, 24290, United States|GSK Investigational Site, Federal Way, Washington, 98003, United States|GSK Investigational Site, Renton, Washington, 98057, United States|GSK Investigational Site, Richland, Washington, 99352, United States|GSK Investigational Site, Selah, Washington, 98942, United States|GSK Investigational Site, Spokane, Washington, 99208, United States|GSK Investigational Site, Spokane, Washington, 99216, United States|GSK Investigational Site, Tacoma, Washington, 98405, United States|GSK Investigational Site, Lewisburg, West Virginia, 24901, United States|GSK Investigational Site, Milwaukee, Wisconsin, 53226, United States|GSK Investigational Site, Villingen-Schwenningen, Baden-Wuerttemberg, 78054, Germany|GSK Investigational Site, Kuenzing, Bayern, 94550, Germany|GSK Investigational Site, Kelkheim, Hessen, 65779, Germany|GSK Investigational Site, Rotenburg, Hessen, 36199, Germany|GSK Investigational Site, Bad Lauterberg, Niedersachsen, 37431, Germany|GSK Investigational Site, Mainz, Rheinland-Pfalz, 55116, Germany|GSK Investigational Site, Berlin, 10115, Germany|GSK Investigational Site, Chaiwan, Hong Kong|GSK Investigational Site, Kwun Tong, Kowloon, Hong Kong|GSK Investigational Site, Shatin, Hong Kong|GSK Investigational Site, Tai Po,, Hong Kong|GSK Investigational Site, Aurangabad, 431001, India|GSK Investigational Site, Bangalore, 560043, India|GSK Investigational Site, Chennai, 600086, India|GSK Investigational Site, Pune, 411 011, India|GSK Investigational Site, Pune, 411011, India|GSK Investigational Site, Callao, Lima, Callao 2, Peru|GSK Investigational Site, Ica, 11, Peru|GSK Investigational Site, Lima, 01, Peru|GSK Investigational Site, Lima, Lima 1, Peru|GSK Investigational Site, Cebu City, 6000, Philippines|GSK Investigational Site, Marikina City, 1810, Philippines|GSK Investigational Site, Quezon City, 1101, Philippines|GSK Investigational Site, Quezon City, 1102, Philippines|GSK Investigational Site, San Juan, 1500, Philippines|GSK Investigational Site, Taytay Rizal, 1920, Philippines|GSK Investigational Site, Smolensk, 214 019, Russian Federation|GSK Investigational Site, Yaroslavl, 150062, Russian Federation|GSK Investigational Site, Alzira/Valencia, 46600, Spain|GSK Investigational Site, Barcelona, 08022, Spain|GSK Investigational Site, Madrid, 28034, Spain|GSK Investigational Site, Palma de Mallorca, 07010, Spain|GSK Investigational Site, Sevilla, 41003, Spain|GSK Investigational Site, Blackpool, Lancashire, FY4 3AD, United Kingdom|GSK Investigational Site, Coventry, West Midlands, CV2 2DX, United Kingdom|GSK Investigational Site, Glasgow, G45 9AW, United Kingdom|GSK Investigational Site, London, SE1 9NH, United Kingdom
URL: https://clinicaltrials.gov/show/NCT00839527

Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress
D089 Metformin small molecule DB00331 Details
D336 Pioglitazone small molecule DB01132 Details