Clinical Trial Details
| Trial ID: | L2353 |
| Source ID: | NCT03380325 |
| Associated Drug: | Iloprost Infusion |
| Title: | The Effect of Iloprost on Capillary Recruitment and Insulin Sensitivity in Type 2 Diabetes |
| Acronym: | |
| Status: | COMPLETED |
| Study Results: | NO |
| Results: | |
| Conditions: | Diabetes Mellitus, Type 2|Insulin Sensitivity/Resistance |
| Interventions: | DRUG: Iloprost infusion |
| Outcome Measures: | Primary: Rate of disappearance, Glucose uptake in peripheral tissues during hyperinsulinemic euglycemic clamp, During the clamp|Capillary recruitment, Change in skeletal muscle en myocardial microvascular blood volume upon insulin infusion, Before and during the clamp | Secondary: Continous cardiovascular monitoring, Diastolic blood pressure, Before and during the clamp|Continous cardiovascular monitoring, Systolic blood pressure, Before and during the clamp|Continous cardiovascular monitoring, Cardiac output, Before and during the clamp|Continous cardiovascular monitoring, Heart rate, Before and during the clamp|Continous cardiovascular monitoring, Stroke volume, Before and during the clamp|Continous cardiovascular monitoring, Systemic vascular resistance, Before and during the clamp |
| Sponsor/Collaborators: | Sponsor: Amsterdam UMC, location VUmc |
| Gender: | ALL |
| Age: | ADULT, OLDER_ADULT |
| Phases: | |
| Enrollment: | 15 |
| Study Type: | INTERVENTIONAL |
| Study Designs: | Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT |
| Start Date: | 2016-05-11 |
| Completion Date: | 2017-06-29 |
| Results First Posted: | |
| Last Update Posted: | 2019-07-18 |
| Locations: | VU University Medical Center, Amsterdam, Noord-Holland, 1081 HV, Netherlands |
| URL: | https://clinicaltrials.gov/show/NCT03380325 |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
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