| Trial ID: | L2403 |
| Source ID: | NCT04426474
|
| Associated Drug: |
Ly3502970
|
| Title: |
A Study of LY3502970 in Participants With Type 2 Diabetes
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes Mellitus, Type 2
|
| Interventions: |
DRUG: LY3502970|DRUG: Placebo
|
| Outcome Measures: |
Primary: Number of Participants with One or More Serious Adverse Event(s) (SAEs) Considered by the Investigator to be Related to Study Drug, A summary of SAEs and other non-serious adverse events (AEs), regardless of causality, will be reported in the Reported Adverse Events module, Baseline through Follow-up (up to Day 105) | Secondary: Pharmacokinetics (PK): Maximum Observed Concentration (Cmax) of LY3502970, PK: Cmax of LY3502970, Day 1 through Day 84: Predose up to 96 hours postdose|PK: Area Under the Concentration Versus Time Curve of LY3502970, PK: AUC of LY3502970, Day 1 through Day 84: Predose up to 96 hours postdose|Pharmacodynamics (PD): Change from Baseline to Week 12 in Fasting Plasma Glucose (FPG), Pharmacodynamics (PD): Change from Baseline to Week 12 in FPG, Baseline, Week 12|PD: Change from Baseline to Week 12 in Fasting Insulin, PD: Change from Baseline to Week 12 in Fasting Insulin, Baseline, Week 12
|
| Sponsor/Collaborators: |
Sponsor: Eli Lilly and Company
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE1
|
| Enrollment: |
68
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2020-10-08
|
| Completion Date: |
2021-07-12
|
| Results First Posted: |
|
| Last Update Posted: |
2021-07-27
|
| Locations: |
Clinical Pharmacology of Miami, Hialeah, Florida, 33014, United States|Hassman Research Institute, Marlton, New Jersey, 08053, United States|Midwest Clinical Research Unit, Dayton, Ohio, 45417, United States|Endeavor Clinical Trials, San Antonio, Texas, 78229, United States|Profil Institut für Stoffwechselforschung, Neuss, Nordrhein-Westfalen, 41460, Germany|Profil Mainz, Mainz, 55116, Germany
|
| URL: |
https://clinicaltrials.gov/show/NCT04426474
|
