| Outcome Measures: |
Primary: Soluble RAGE concentration, Before and after the intervention using the serum extracted from the patient using sandwich ELISA., 90 days | Secondary: Glomerular filtration rate, Before and after the intervention, it will be evaluated by means of a determination of serum creatinine, which will be analyzed with the spectrophotometry method and from its result the glomerular filtration rate is calculated., 90 days|Albumin/creatinine ratio, Before and after intervention by spectrophotometry, 90 days|Fasting plasma glucose, Before and after intervention spectrophotometry, 90 days|Glycated Hemoglobin concentration, It will be analyzed by liquid chromatography, 90 days|Systolic and diastolic arterial pressure, Before and after intervention using a digital baumanometer, 90 days|Alanine aminotransferase, Before and after intervention by spectrophotometry, 90 days|Aspartate aminotransferase, Before and after intervention by spectrophotometry, 90 days | Other: Total cholesterol, Before and after intervention by spectrophotometry, 90 days|triglycerides, Before and after intervention by spectrophotometry, 90 days|High-density lipoprotein cholesterol, Before and after intervention by spectrophotometry, 90 days|Low-density lipoprotein cholesterol, Before and after intervention by friedewall formula, 90 days|Weight and visceral fat %, Before and after intervention using a vascula of impedance, 90 days
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