| Trial ID: | L2572 |
| Source ID: | NCT01028846
|
| Associated Drug: |
Diazoxide
|
| Title: |
Central Mechanisms That Regulate Glucose Metabolism in Humans
|
| Acronym: |
|
| Status: |
TERMINATED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT01028846/results
|
| Conditions: |
Type 2 Diabetes|Glucose Metabolism Disorders|Glucose, High Blood
|
| Interventions: |
DRUG: Diazoxide|DRUG: Placebo
|
| Outcome Measures: |
Primary: Rate of Endogenous Glucose Production (EGP), Rate of EGP (a measure of the body's production of sugar) was measured using analysis of blood samples taken throughout the pancreatic clamp procedure under various treatment conditions (e.g., diazoxide or placebo) by monitoring changes in the level of a non-radioactive, naturally occurring form of glucose (sugar). Rates were summarized by treatment (Diazoxide or Placebo) in mg/kg/min sing basic descriptive statistics., Final 60 minutes (t=180-240 minutes) of the pancreatic clamp, 6-7 hours after dosing |
|
| Sponsor/Collaborators: |
Sponsor: Meredith Hawkins | Collaborators: National Institutes of Health (NIH)|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)|American Diabetes Association
|
| Gender: |
ALL
|
| Age: |
ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
10
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2006-11-02
|
| Completion Date: |
2007-12-05
|
| Results First Posted: |
2025-03-14
|
| Last Update Posted: |
2025-03-14
|
| Locations: |
Albert Einstein College of Medicine, Bronx, New York, 10461, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT01028846
|
