CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Clinical Trial Details

Trial ID:	L2580
Source ID:	NCT01046110
Associated Drug:	Insulin Degludec
Title:	Comparison of NN1250 With Sitagliptin in Subjects With Type 2 Diabetes Never Treated With Insulin
Acronym:	BEGIN™
Status:	COMPLETED
Study Results:	YES
Results:	https://ClinicalTrials.gov/show/NCT01046110/results
Conditions:	Diabetes\|Diabetes Mellitus, Type 2
Interventions:	DRUG: insulin degludec\|DRUG: sitagliptin
Outcome Measures:	Primary: Change in Glycosylated Haemoglobin (HbA1c), Change from baseline in HbA1c after 26 weeks of treatment, Week 0, Week 26 \| Secondary: Change in Fasting Plasma Glucose (FPG), Change from baseline in FPG after 26 weeks of treatment, Week 0, Week 26
Sponsor/Collaborators:	Sponsor: Novo Nordisk A/S
Gender:	ALL
Age:	ADULT, OLDER_ADULT
Phases:	PHASE3
Enrollment:	458
Study Type:	INTERVENTIONAL
Study Designs:	Allocation: RANDOMIZED\|Intervention Model: PARALLEL\|Masking: NONE\|Primary Purpose: TREATMENT
Start Date:	2010-01
Completion Date:	2010-11
Results First Posted:	2015-11-18
Last Update Posted:	2017-03-03
Locations:	Novo Nordisk Investigational Site, Huntsville, Alabama, 35801, United States\|Novo Nordisk Investigational Site, Concord, California, 94520, United States\|Novo Nordisk Investigational Site, Fresno, California, 93720, United States\|Novo Nordisk Investigational Site, Greenbrae, California, 94904, United States\|Novo Nordisk Investigational Site, La Jolla, California, 92037, United States\|Novo Nordisk Investigational Site, Long Beach, California, 90806, United States\|Novo Nordisk Investigational Site, Mission Hills, California, 91345, United States\|Novo Nordisk Investigational Site, Palm Springs, California, 92262, United States\|Novo Nordisk Investigational Site, Torrance, California, 90504, United States\|Novo Nordisk Investigational Site, Walnut Creek, California, 94598-3347, United States\|Novo Nordisk Investigational Site, Denver, Colorado, 80239-3133, United States\|Novo Nordisk Investigational Site, Clearwater, Florida, 33765, United States\|Novo Nordisk Investigational Site, Inverness, Florida, 34452, United States\|Novo Nordisk Investigational Site, Kissimmee, Florida, 34741, United States\|Novo Nordisk Investigational Site, Miami, Florida, 33125-1655, United States\|Novo Nordisk Investigational Site, Miami, Florida, 33135, United States\|Novo Nordisk Investigational Site, Miami, Florida, 33186, United States\|Novo Nordisk Investigational Site, Ocala, Florida, 34471, United States\|Novo Nordisk Investigational Site, Ponte Vedra, Florida, 32081, United States\|Novo Nordisk Investigational Site, Tampa, Florida, 33603, United States\|Novo Nordisk Investigational Site, Columbus, Georgia, 31904, United States\|Novo Nordisk Investigational Site, Decatur, Georgia, 30033, United States\|Novo Nordisk Investigational Site, Dunwoody, Georgia, 30338, United States\|Novo Nordisk Investigational Site, Roswell, Georgia, 30076, United States\|Novo Nordisk Investigational Site, Chicago, Illinois, 60611, United States\|Novo Nordisk Investigational Site, Chicago, Illinois, 60624, United States\|Novo Nordisk Investigational Site, Springfield, Illinois, 62711, United States\|Novo Nordisk Investigational Site, Huntington, Indiana, 46750-1404, United States\|Novo Nordisk Investigational Site, Council Bluffs, Iowa, 51501, United States\|Novo Nordisk Investigational Site, Des Moines, Iowa, 50314-2610, United States\|Novo Nordisk Investigational Site, Paducah, Kentucky, 42003, United States\|Novo Nordisk Investigational Site, Metairie, Louisiana, 70002, United States\|Novo Nordisk Investigational Site, Brockton, Massachusetts, 02301, United States\|Novo Nordisk Investigational Site, Livonia, Michigan, 48152-3501, United States\|Novo Nordisk Investigational Site, Troy, Michigan, 48085-5524, United States\|Novo Nordisk Investigational Site, St. Paul, Minnesota, 55108, United States\|Novo Nordisk Investigational Site, Jackson, Mississippi, 39216, United States\|Novo Nordisk Investigational Site, Albuquerque, New Mexico, 87108, United States\|Novo Nordisk Investigational Site, Albuquerque, New Mexico, 87131, United States\|Novo Nordisk Investigational Site, New Hyde Park, New York, 11042, United States\|Novo Nordisk Investigational Site, West Seneca, New York, 14224, United States\|Novo Nordisk Investigational Site, Durham, North Carolina, 27710, United States\|Novo Nordisk Investigational Site, Greenville, North Carolina, 27834-5784, United States\|Novo Nordisk Investigational Site, Oklahoma City, Oklahoma, 73104, United States\|Novo Nordisk Investigational Site, Pittsburgh, Pennsylvania, 15224-2215, United States\|Novo Nordisk Investigational Site, Pittsburgh, Pennsylvania, 15241, United States\|Novo Nordisk Investigational Site, Charleston, South Carolina, 29401, United States\|Novo Nordisk Investigational Site, Murrells Inlet, South Carolina, 29576, United States\|Novo Nordisk Investigational Site, Corpus Christi, Texas, 78404, United States\|Novo Nordisk Investigational Site, El Paso, Texas, 79905-2709, United States\|Novo Nordisk Investigational Site, El Paso, Texas, 79912, United States\|Novo Nordisk Investigational Site, Houston, Texas, 77070, United States\|Novo Nordisk Investigational Site, Sugar Land, Texas, 77478, United States\|Novo Nordisk Investigational Site, Tomball, Texas, 77375, United States\|Novo Nordisk Investigational Site, Salt Lake City, Utah, 84107, United States\|Novo Nordisk Investigational Site, Virginia Beach, Virginia, 23454, United States\|Novo Nordisk Investigational Site, Spokane, Washington, 99208, United States\|Novo Nordisk Investigational Site, Buenos Aires, C1181ACH, Argentina\|Novo Nordisk Investigational Site, Caba, C1440AAD, Argentina\|Novo Nordisk Investigational Site, Ciudad Autónoma de BsAs, C1406FWY, Argentina\|Novo Nordisk Investigational Site, Córdoba, 5000, Argentina\|Novo Nordisk Investigational Site, Mar del Plata, B7602CBM, Argentina\|Novo Nordisk Investigational Site, Mendoza, 5500, Argentina\|Novo Nordisk Investigational Site, Surrey, British Columbia, V3S 2N6, Canada\|Novo Nordisk Investigational Site, Cambridge, Ontario, N1R 7L6, Canada\|Novo Nordisk Investigational Site, Chatham, Ontario, N7L 1C1, Canada\|Novo Nordisk Investigational Site, London, Ontario, N6H 4P2, Canada\|Novo Nordisk Investigational Site, London, Ontario, N6P 1A9, Canada\|Novo Nordisk Investigational Site, Smiths Falls, Ontario, K7A 4W8, Canada\|Novo Nordisk Investigational Site, St.Catharines, Ontario, L2N 7H8, Canada\|Novo Nordisk Investigational Site, Gatineau, Quebec, J8V 2P5, Canada\|Novo Nordisk Investigational Site, Laval, Quebec, H7T 2P5, Canada\|Novo Nordisk Investigational Site, Montreal, Quebec, H3J 2V5, Canada\|Novo Nordisk Investigational Site, St-Marc-des-Carrières, Quebec, G0A 4B0, Canada\|Novo Nordisk Investigational Site, Hyderabad, Andhra Pradesh, 500 001, India\|Novo Nordisk Investigational Site, Bangalore, Karnataka, 560 003, India\|Novo Nordisk Investigational Site, Bangalore, Karnataka, BANGALORE, India\|Novo Nordisk Investigational Site, Mumbai, Maharashtra, 400008, India\|Novo Nordisk Investigational Site, Chennai, Tamil Nadu, 600029, India\|Novo Nordisk Investigational Site, Madurai, Tamil Nadu, 625 020, India\|Novo Nordisk Investigational Site, Nagpur, 440012, India\|Novo Nordisk Investigational Site, Pune, 411005, India\|Novo Nordisk Investigational Site, Pune, 411011, India\|Novo Nordisk Investigational Site, Guadalajara, 44600, Mexico\|Novo Nordisk Investigational Site, Mexico City, 11850, Mexico\|Novo Nordisk Investigational Site, Durban, KwaZulu-Natal, 4001, South Africa\|Novo Nordisk Investigational Site, Cape Town, Western Cape, 7460, South Africa\|Novo Nordisk Investigational Site, Umhlanga, 4320, South Africa\|Novo Nordisk Investigational Site, Ankara, 06100, Turkey\|Novo Nordisk Investigational Site, Denizli, 20070, Turkey\|Novo Nordisk Investigational Site, Istanbul, 34098, Turkey\|Novo Nordisk Investigational Site, Istanbul, 34390, Turkey\|Novo Nordisk Investigational Site, Izmir, 35340, Turkey
URL:	https://clinicaltrials.gov/show/NCT01046110

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Associated Data

Drug ID	Drug Name	Type	DrugBank ID	Targets	Category	Latest Progress

Clinical Trial Details

Summary

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Associated Data

Associated NAFLD Drugs (0)