| Trial ID: | L2698 |
| Source ID: | NCT02105792
|
| Associated Drug: |
Second- Or Third-Line Glucose-Lowering Diabetes Treatment
|
| Title: |
PROMASTER - PROspective Cohort MRC ABPI STratification and Extreme Response Mechanism in Diabetes
|
| Acronym: |
PROMASTER
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes
|
| Interventions: |
DRUG: second- or third-line glucose-lowering diabetes treatment
|
| Outcome Measures: |
Primary: Response to diabetes therapy, The primary outcome will be to compare the clinical characteristics of the patients who show an excellent response or a poor response to specific second- and third-line classes of treatment for Type 2 diabetes., Up to 9 months from commencement of new therapy | Secondary: Collection of samples for analysis of potential biomarkers, To collect a set of DNA, serum and urine samples to allow analysis of potential genetic and non genetic biomarkers for drug response and diabetes progression., within 9 months of recruitment date
|
| Sponsor/Collaborators: |
Sponsor: Royal Devon and Exeter NHS Foundation Trust | Collaborators: University of Exeter|King's College London|King's College Hospital NHS Trust|University of Glasgow|NHS Greater Glasgow and Clyde|Newcastle University|Newcastle-upon-Tyne Hospitals NHS Trust|Oxford University Hospitals NHS Trust
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
|
| Enrollment: |
820
|
| Study Type: |
OBSERVATIONAL
|
| Study Designs: |
Observational Model: |Time Perspective: p
|
| Start Date: |
2013-03
|
| Completion Date: |
2016-05
|
| Results First Posted: |
|
| Last Update Posted: |
2018-06-21
|
| Locations: |
University of Exeter, Exeter, Devon, EX2 5DW, United Kingdom|Oxford University Hospitals NHS Trust, Oxford, Oxfordshire, OX3 7LE, United Kingdom|University of Newcastle, Newcastle upon Tyne, Tyne And Wear, NE1 7RU, United Kingdom|University of Glasgow, Glasgow, G12 8TA, United Kingdom|King's College University of London, London, SE1 9NH, United Kingdom
|
| URL: |
https://clinicaltrials.gov/show/NCT02105792
|
