| Trial ID: | L3056 |
| Source ID: | NCT01319357
|
| Associated Drug: |
Saxagliptin
|
| Title: |
Effects of Saxagliptin on Endothelial Function
|
| Acronym: |
ESENDI
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes Mellitus Type 2
|
| Interventions: |
DRUG: Saxagliptin|DRUG: Placebo
|
| Outcome Measures: |
Primary: effect of saxagliptin compared to placebo on endothelial and vascular function of the retinal circulation, retinal circulation. By applying Scanning-Laser-Doppler-Flowmetry, the change of retinal capillary flow after i.v. L-NMMA application, after 6 weeks of treatment with saxagliptin vs. 6 weeks of treatment with placebo (12 weeks in all) |
|
| Sponsor/Collaborators: |
Sponsor: University of Erlangen-Nürnberg Medical School
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE3
|
| Enrollment: |
52
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2010-10
|
| Completion Date: |
2013-04
|
| Results First Posted: |
|
| Last Update Posted: |
2014-02-12
|
| Locations: |
Clinical Research Center, Department of Nephrology and Hypertension, University of Erlangen-Nuremberg, Erlangen, 91054, Germany
|
| URL: |
https://clinicaltrials.gov/show/NCT01319357
|
