| Trial ID: | L3099 |
| Source ID: | NCT02291666
|
| Associated Drug: |
Crchum-Mt Cocktail
|
| Title: |
Evaluation of CYP450 Activities in Diabetic Patients vs. Non-diabetic Subjects
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes
|
| Interventions: |
DRUG: CRCHUM-MT cocktail
|
| Outcome Measures: |
Primary: Metabolic ratio, The metabolite/probe-drug (parent compound) ratio will be used as a metabolic index of CYP activity., 12 hours | Secondary: Oral clearance, CLo will be determined by noncompartmental analysis, 12 hours|Renal clearance, CLr will be determined by noncompartmental analysis (Ae0-t of compound/AUC0-t compound), 12 hours
|
| Sponsor/Collaborators: |
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) | Collaborators: Canadian Institutes of Health Research (CIHR)
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
73
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2015-04
|
| Completion Date: |
2019-07
|
| Results First Posted: |
|
| Last Update Posted: |
2019-07-23
|
| Locations: |
Centre hospitalier de l'Université de Montréal (CHUM), Montreal, Quebec, H2X0A9, Canada
|
| URL: |
https://clinicaltrials.gov/show/NCT02291666
|
