| Outcome Measures: |
Primary: Change From Baseline in Hemoglobin A1c (HbA1c), HbA1c is the glycosylated fraction of hemoglobin A. HbA1c is measured to identify average plasma glucose concentration over prolonged periods of time. Least Squares (LS) mean was determined by mixed model repeated measures (MMRM) model with Baseline + Oral Antihyperglycemic Medications (OAM) use + Treatment + Visit + Treatment\*Visit (Type III sum of squares) as variables., Baseline, Week 28 | Secondary: Percentage of Participants Achieving HbA1c <7.0%, HbA1c is the glycosylated fraction of hemoglobin A. HbA1c is measured to identify average plasma glucose concentration over prolonged periods of time. Odds Ratio (OR) was determined using longitudinal logistic regression model with Baseline HbA1c value + OAM use + Treatment + Visit + Treatment\*Visit as variables., Week 28|Change From Baseline in Body Weight, Change from baseline in body weight was reported here. LS mean was determined by MMRM model with Baseline + Baseline HbA1c strata (\<8.5%, \>=8.5%) + OAM use + Treatment + Visit + Treatment\*Visit (Type III sum of squares) as variables., Baseline, Week 28|Change From Baseline in Fasting Serum Glucose (FSG), Change from baseline in FSG was reported here. LS mean was determined using MMRM model with Baseline + Baseline HbA1c strata (\<8.5%, \>=8.5%) + OAM use + Treatment + Visit + Treatment\*Visit (Type III sum of squares) as variables., Baseline, Week 28|Percentage of Participants Achieving HbA1c <7.0% With no Weight Gain (<0.1 kg) and Without Documented Symptomatic Hypoglycemia (Blood Glucose <3.0 mmol/L), Percentage of Participants Achieving HbA1c \<7.0% With no Weight Gain (\<0.1 kg) and Without Documented Symptomatic Hypoglycemia (Blood Glucose \<3.0 mmol/L) was reported here., Week 28|Percentage of Participants Achieving HbA1c <7.0% Without Documented Symptomatic Hypoglycemia (Blood Glucose <3.0 mmol/L), Percentage of Participants Achieving HbA1c \<7.0% Without Documented Symptomatic Hypoglycemia (Blood Glucose \<3.0 mmol/L) was reported here., Week 28|Percentage of Participants Achieving HbA1c <7.0% Without Weight Gain (<0.1 kg), Percentage of Participants Achieving HbA1c \<7.0% Without Weight Gain (\<0.1 kg) was reported here., Week 28|Change From Baseline in Blood Glucose From Daily Self-Monitored Blood Glucose (SMBG) Profile, The SMBG data was collected at the following 7 time points: Pre morning meal BG, 2-hour postprandial measurement for morning meal BG, Pre midday meal BG, 2-hour postprandial measurement for midday meal BG, Pre evening meal BG, 2-hour postprandial measurement for evening meals BG, and Bedtime BG. LS mean was determined using MMRM model with Baseline + OAM (metformin and/or acarbose) usage + HbA1c Group at Baseline + Treatment + Time + Treatment\*Time (Type III sum of squares) as variables., Baseline, Week 28|Change From Baseline in Daily Mean Insulin Glargine Doses, LS mean was determined using MMRM model with Baseline + Baseline HbA1c strata (\<8.5%, \>=8.5%) + OAM use + Treatment + Visit + Treatment\*Visit (Type III sum of squares) as variables., Baseline, Week 28
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| Locations: |
The Second People's Hospital of Hefei, Hefei, Anhui, 230011, China|Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510120, China|First Affiliated Hospital of the Harbin Medical University, Harbin, Heilongjiang, 150001, China|The Fourth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, China|The First Affiliated Hospital of Henan University of Science &Technology, Luoyang Shi, Henan, 471003, China|The Second Affiliated Hospital of Zhengzhou University, Zhengzhou Shi, Henan, 450014, China|Changzhou No.2 People's Hospital, Changzhou, Jiangsu, 213003, China|Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, 210000, China|The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China|The First Hospital of Nanjing, Nanjing, Jiangsu, 210012, China|Nanjing Medical University - Nanjing Jiangning Hospital, Nanjing, Jiangsu, 211100, China|No. 2 Affiliated Hospital of Suzhou University, Suzhou Shi, Jiangsu, 215004, China|Wuxi People's Hospital, Wuxi, Jiangsu, 214023, China|The Third Hospital of Nanchang, Nanchang, Jiangxi, 330009, China|Pingxiang People's Hospital, Pingxiang, Jiangxi, 337000, China|The First Hospital of Jilin University, Changchun, Jilin, 130021, China|Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, Liaoning, 116033, China|Jinan Central Hospital, Jinan, Shandong, 250013, China|Shanghai Putuo District Center Hospital, Shanghai, Shanghai, 200062, China|The First Affiliated Hospital of Xi'an Medical University, XI 'an, Shanxi, 710077, China|West China Hospital Sichuan University, Chengdu, Sichuan, 610041, China|Tianjin Medical University General Hospital, Tianjin, Tianjin, 300052, China|The Affiliated Jiangyin Hospital of Southeast University Medical College, Wuxi Shi, Wuxi Shi, 214400, China|The First People's Hospital of Yunnan Province, Kunming, Yunnan, 650034, China|Chongqing General Hospital, Chongqing, Yuzhong District, 400014, China|Zhejiang Hospital, Hangzhou, Zhejiang, 310013, China|Beijing Pinggu District Hospital, Beijing, 101200, China
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