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Clinical Trial Details

Trial ID: L0320
Source ID: NCT05432167
Associated Drug: Cin-107
Title: A Study to Evaluate CIN-107 for the Treatment of Patients With Uncontrolled Hypertension and Chronic Kidney Disease
Acronym:
Status: COMPLETED
Study Results: NO
Results:
Conditions: Uncontrolled Hypertension|Chronic Kidney Diseases
Interventions: DRUG: CIN-107|DRUG: Placebo
Outcome Measures: Primary: Change from baseline in mean seated systolic blood pressure (SBP), Change in mean seated SBP from baseline to Week 26 in patients receiving CIN-107 compared to placebo., At Week 26 | Secondary: Change from baseline in SBP in CIN-107 compared to placebo in patients assigned to the high-dose strategy group, Change in mean seated SBP from baseline to Week 26 in patients receiving high-dose CIN-107 compared to placebo, At Week 26|Change from baseline of SBP in CIN-107 compared to placebo in patients assigned to the low-dose strategy group, Change in mean seated SBP from baseline to Week 26 in patients receiving low-dose CIN-107 compared to placebo, At Week 26
Sponsor/Collaborators: Sponsor: AstraZeneca | Collaborators: Parexel
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases: PHASE2
Enrollment: 194
Study Type: INTERVENTIONAL
Study Designs: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Start Date: 2022-04-29
Completion Date: 2024-05-02
Results First Posted:
Last Update Posted: 2024-08-26
Locations: Research Site, Birmingham, Alabama, 35209, United States|Research Site, Huntsville, Alabama, 35805, United States|Research Site, Beverly Hills, California, 90211, United States|Research Site, Chula Vista, California, 91910, United States|Research Site, Fountain Valley, California, 92708, United States|Research Site, Granada Hills, California, 91344, United States|Research Site, Lincoln, California, 95648, United States|Research Site, Los Angeles, California, 90010, United States|Research Site, Lynwood, California, 90262, United States|Research Site, Northridge, California, 91324, United States|Research Site, Panorama City, California, 91402, United States|Research Site, Pomona, California, 91767, United States|Research Site, Rancho Cucamonga, California, 91730, United States|Research Site, Riverside, California, 92503, United States|Research Site, S. Gate, California, 90280, United States|Research Site, San Dimas, California, 91773, United States|Research Site, Tarzana, California, 91356, United States|Research Site, Vacaville, California, 95687, United States|Research Site, Victorville, California, 92392, United States|Research Site, Arvada, Colorado, 80002, United States|Research Site, Littleton, Colorado, 80120, United States|Research Site, Hollywood, Florida, 33021, United States|Research Site, Orlando, Florida, 32807, United States|Research Site, Orlando, Florida, 32808, United States|Research Site, Tampa, Florida, 33612, United States|Research Site, West Palm Beach, Florida, 33401, United States|Research Site, Columbus, Georgia, 31904, United States|Research Site, Decatur, Georgia, 30030, United States|Research Site, Suwanee, Georgia, 30024, United States|Research Site, Nampa, Idaho, 83687, United States|Research Site, Chicago, Illinois, 60643, United States|Research Site, Brownsburg, Indiana, 46112, United States|Research Site, Lexington, Kentucky, 40503, United States|Research Site, Metairie, Louisiana, 70006, United States|Research Site, Monroe, Louisiana, 71201, United States|Research Site, New Bedford, Massachusetts, 02740, United States|Research Site, Flint, Michigan, 48504, United States|Research Site, Flint, Michigan, 48532, United States|Research Site, Troy, Michigan, 48085, United States|Research Site, Olive Branch, Mississippi, 38654, United States|Research Site, Kansas City, Missouri, 64111, United States|Research Site, Trenton, New Jersey, 08611, United States|Research Site, Bronx, New York, 10455, United States|Research Site, Charlotte, North Carolina, 28208, United States|Research Site, Durham, North Carolina, 27704, United States|Research Site, Greenville, North Carolina, 27834, United States|Research Site, Kinston, North Carolina, 28504, United States|Research Site, Morganton, North Carolina, 28655, United States|Research Site, Oxford, North Carolina, 27565, United States|Research Site, Wilmington, North Carolina, 28401, United States|Research Site, Cincinnati, Ohio, 45246, United States|Research Site, Bethany, Oklahoma, 73008, United States|Research Site, Scottdale, Pennsylvania, 15683, United States|Research Site, Smithfield, Pennsylvania, 15478, United States|Research Site, Providence, Rhode Island, 02903, United States|Research Site, Memphis, Tennessee, 38119, United States|Research Site, Houston, Texas, 77099, United States|Research Site, Lampasas, Texas, 76550, United States|Research Site, McAllen, Texas, 78503, United States|Research Site, Paris, Texas, 75462, United States|Research Site, Red Oak, Texas, 75154, United States|Research Site, San Antonio, Texas, 78212, United States|Research Site, San Antonio, Texas, 78249, United States|Research Site, Webster, Texas, 77598, United States|Research Site, Salt Lake City, Utah, 84132, United States|Research Site, Burlington, Vermont, 05401, United States|Research Site, Alexandria, Virginia, 22304, United States|Research Site, Burke, Virginia, 22015, United States|Research Site, Charlottesville, Virginia, 22908, United States|Research Site, Manassas, Virginia, 20110, United States|Research Site, Newport News, Virginia, 23606, United States|Research Site, Salem, Virginia, 24153, United States|Research Site, Kingwood, West Virginia, 26537, United States
URL: https://clinicaltrials.gov/show/NCT05432167

Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress