| Trial ID: | L3231 |
| Source ID: | NCT01441986
|
| Associated Drug: |
Dextromethorphan Hydrobromide
|
| Title: |
Dextromethorphan, Amantadine and Glucose Homeostasis in Diabetes Subjects
|
| Acronym: |
DXM/AMT
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes Mellitus
|
| Interventions: |
DRUG: Dextromethorphan hydrobromide|DRUG: Amantadine|DRUG: Pacebo 1 (placebo for Amantadine)|DRUG: Placebo 2 (fo Dextromethorphan)
|
| Outcome Measures: |
Primary: Area under the blood glucose (BG) concentration-time profile, from 1-3 hours post-dose (i.e. from 0-2 hours after an OGTT) | Secondary: Area under the blood glucose concentration-time profile, 0-1 hour post-dose (i.e. before starting the OGTT)|Adverse events, 5 hours post-dose
|
| Sponsor/Collaborators: |
Sponsor: Profil Institut für Stoffwechselforschung GmbH | Collaborators: Heinrich-Heine University, Duesseldorf
|
| Gender: |
MALE
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE2
|
| Enrollment: |
20
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2011-09
|
| Completion Date: |
2012-05
|
| Results First Posted: |
|
| Last Update Posted: |
2012-07-12
|
| Locations: |
Profil Institute for Metabolic Research, Neuss, NRW, 41460, Germany
|
| URL: |
https://clinicaltrials.gov/show/NCT01441986
|
