| Trial ID: | L3300 |
| Source ID: | NCT00886366
|
| Associated Drug: |
Azd6714
|
| Title: |
Single Ascending Dose Study With Healthy Male Volunteers and Type II Diabetic Patients
|
| Acronym: |
|
| Status: |
TERMINATED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes
|
| Interventions: |
DRUG: AZD6714|DRUG: Placebo|DRUG: AZD6714|DRUG: AZD6714
|
| Outcome Measures: |
Primary: Safety variables (AE, BP, pulse, plasma glucose, laboratory variables and ECG), AEs will be collected during the whole study period (1-3 months). The other variables will be measured repeatedly during 24 hours on the study day sessions | Secondary: Pharmacokinetic variables, Blood samples taken repeatedly during 24 hours on study day sessions.|Pharmacodynamic variables (P-Glucose, S-Insulin and C-peptide), Blood samples taken repeatedly during 24 hours on study day sessions.
|
| Sponsor/Collaborators: |
Sponsor: AstraZeneca
|
| Gender: |
ALL
|
| Age: |
ADULT
|
| Phases: |
PHASE1
|
| Enrollment: |
26
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
|
| Start Date: |
2009-04
|
| Completion Date: |
2009-09
|
| Results First Posted: |
|
| Last Update Posted: |
2010-12-07
|
| Locations: |
Research Site, Goteborg, Sweden
|
| URL: |
https://clinicaltrials.gov/show/NCT00886366
|
