Clinical Trial Details
| Trial ID: | L0332 |
| Source ID: | NCT02511418 |
| Associated Drug: | Simvastatin |
| Title: | Renal Hemodynamic Effects of the HMG-CoA Reductase Inhibitors in Normal Volunteers and in Patients With Chronic Renal Failure |
| Acronym: | |
| Status: | COMPLETED |
| Study Results: | NO |
| Results: | |
| Conditions: | Hyperlipidemia|Hypertension|Chronic Renal Failure |
| Interventions: | DRUG: Simvastatin |
| Outcome Measures: | Primary: Effect of short term HMG-CoA reductase treatment, Differences between mean values for RPF, GFR and FF at baseline versus mean values obtained for these same parameters after 4 weeks of treatment will be analyzed using two-tailed Student's paired t-test. A similar analysis will be performed regarding patient's profiles for creatinine clearance, serum creatinine, urinary protein excretion and serum lipids. All results will be expressed as mean ± standard deviations. Differences will be considered significant at P \<0.05., 4 weeks | |
| Sponsor/Collaborators: | Sponsor: Mayo Clinic |
| Gender: | ALL |
| Age: | ADULT, OLDER_ADULT |
| Phases: | |
| Enrollment: | |
| Study Type: | INTERVENTIONAL |
| Study Designs: | Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT |
| Start Date: | |
| Completion Date: | |
| Results First Posted: | |
| Last Update Posted: | 2023-03-16 |
| Locations: | |
| URL: | https://clinicaltrials.gov/show/NCT02511418 |
