| Trial ID: | L3385 |
| Source ID: | NCT01588366
|
| Associated Drug: |
Placebo
|
| Title: |
The Effects of LY2409021 on the Liver
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT01588366/results
|
| Conditions: |
Diabetes Mellitus, Type 2
|
| Interventions: |
DRUG: Placebo|DRUG: LY2409021
|
| Outcome Measures: |
Primary: Change From Baseline to Day 28 in Liver Fat Average Percent (%), Measured by magnetic resonance (MR) scanning., Baseline, Day 28 (Pre-meal)|Change From Baseline to Day 28 in Hepatic Glycogen Content, Measured by MR scanning., Baseline, Day 28 (Pre-meal) | Secondary: Change From Baseline to Day 28 in Transaminase Levels, Baseline, Day 28|Change From Baseline to Day 29 in Glucose Response to an Arginine Stimulation Test (AST) (Part A), Acute glucose response to an AST at a blood glucose level of approximately 250 milligrams per deciliter (mg/dL)., Baseline, Day 29|Change From Baseline to Day 29 in Glucagon Response to an Arginine Stimulation Test (AST) (Part A), Acute glucagon response to an AST at a blood glucose level of approximately 250 mg/dL., Baseline, Day 29|Change From Baseline to Day 29 in Insulin Response to an Arginine Stimulation Test (AST) (Part A), Acute insulin response to an AST at a blood glucose level of approximately 250 mg/dL., Baseline, Day 29
|
| Sponsor/Collaborators: |
Sponsor: Eli Lilly and Company
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE1
|
| Enrollment: |
30
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2012-04
|
| Completion Date: |
2013-09
|
| Results First Posted: |
2019-03-07
|
| Last Update Posted: |
2019-03-07
|
| Locations: |
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST) or speak with your personal physician., Singapore, Singapore
|
| URL: |
https://clinicaltrials.gov/show/NCT01588366
|
