| Trial ID: | L3402 |
| Source ID: | NCT05730634
|
| Associated Drug: |
Atorvastatin 40 Mg Oral Tablet
|
| Title: |
The Effect of Statin Treatment on Arterial Wall Inflammation as Assessed With 68Ga-DOTATATE PET-CT
|
| Acronym: |
CARAMEL
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes Mellitus, Type 2|Vascular Inflammation
|
| Interventions: |
DRUG: Atorvastatin 40 Mg Oral Tablet
|
| Outcome Measures: |
Primary: DOTATATE coronary arteries, Change in DOTATATE TBRmax coronary arteries after atorvastatin therapy, 3 months | Secondary: Change in splenic/bone marrow DOTATATE signal, The secondary objective of this study is to assess the feasibility to measure splenic and bone-marrow inflammatory activity with 68Ga-Dotatate PET-CT in patients with diabetes mellitus, expressed as SUVmax, 3 month
|
| Sponsor/Collaborators: |
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
|
| Enrollment: |
24
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
|
| Start Date: |
2019-06-01
|
| Completion Date: |
2022-05-06
|
| Results First Posted: |
|
| Last Update Posted: |
2023-02-16
|
| Locations: |
Amsterdam UMC, location AMC, Amsterdam, Noord-Holland, 1105AZ, Netherlands
|
| URL: |
https://clinicaltrials.gov/show/NCT05730634
|
