| Trial ID: | L3742 |
| Source ID: | NCT01084369
|
| Associated Drug: |
Testosterone
|
| Title: |
Effect of Testosterone on Endothelial Function and Microcirculation in Type 2 Diabetic Patients With Hypogonadism
|
| Acronym: |
|
| Status: |
TERMINATED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes|Hypogonadism
|
| Interventions: |
DRUG: Testosterone
|
| Outcome Measures: |
Primary: Improvement in endothelial dependent and endothelial-independent vasodilatation, Improvement in markers of endothelial function, 30 and 54 weeks | Secondary: Markers of endothelial function, Secondary efficacy variables will include changes of the following * Availability of nitric oxide * Endothelial inflammation as measured by CRP * Serum levels of endothelial markers: IGF and adhesion molecules * BMI, waist circumference, glycaemic control (HbA1c), lipid profile and blood pressure. * Other laboratory parameters, 54 weeks
|
| Sponsor/Collaborators: |
Sponsor: Tameside Hospital NHS Foundation Trust
|
| Gender: |
MALE
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
22
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2013-10-11
|
| Completion Date: |
2014-09-14
|
| Results First Posted: |
|
| Last Update Posted: |
2019-04-04
|
| Locations: |
Tameside General Hospital, Ashton-under-Lyne, Lancashire, OL6 9RW, United Kingdom|Tameside Hospital NHS Foundatoin Trust, Ashton under Lyne, OL69RW, United Kingdom
|
| URL: |
https://clinicaltrials.gov/show/NCT01084369
|
