| Trial ID: | L3775 |
| Source ID: | NCT01434901
|
| Associated Drug: |
Placebo
|
| Title: |
The Effects of Bethanechol on Glucose Homeostasis
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes Mellitus
|
| Interventions: |
DRUG: Placebo|DRUG: Bethanechol (25 mg)|DRUG: Bethanechol (50 mg)|DRUG: Bethanechol (100 mg)
|
| Outcome Measures: |
Primary: The effects of Bethanechol on insulin secretion rates, Insulin secretion rates (pmoles/min) will be calculated by deconvolution of plasma C-peptide levels. The investigators will then determine if post-prandial insulin secretion rates are greater following administration of Bethanechol compared to placebo., 3 years |
|
| Sponsor/Collaborators: |
Sponsor: Washington University School of Medicine | Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE1
|
| Enrollment: |
50
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2011-08-15
|
| Completion Date: |
2014-07-07
|
| Results First Posted: |
|
| Last Update Posted: |
2018-05-08
|
| Locations: |
Washington University School of Medicine, Saint Louis, Missouri, 63131, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT01434901
|
