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Clinical Trial Details

Trial ID: L3791
Source ID: NCT06065540
Associated Drug: Cagrilintide
Title: A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
Acronym: REIMAGINE 2
Status: ACTIVE_NOT_RECRUITING
Study Results: NO
Results:
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Cagrilintide|DRUG: Semaglutide|DRUG: Placebo cagrilintide|DRUG: Placebo semaglutide
Outcome Measures: Primary: CagriSema (dose 1) versus semaglutide (dose 1): Change in glycated haemoglobin (HbA1c), Measured in percentage-points., From baseline (week 0) to end of treatment (week 68) | Secondary: CagriSema versus cagrilintide: Change in HbA1c, Measured in percentage-points., From baseline (week 0) to end of treatment (week 68)|CagriSema versus cagrilintide: Relative change in body weight, Measured in percentage., From baseline (week 0) to end of treatment (week 68)|CagriSema (dose 1) versus semaglutide (dose 2): Change in HbA1c, Measured in percentage-points., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Relative change in body weight, Measured in percentage., From baseline (week 0) to end of treatment (week 68)|Cagrilintide versus placebo: Change in HbA1c, Measured in percentage-points., From baseline (week 0) to end of treatment (week 68)|Cagrilintide versus placebo: Relative change in body weight, Measured in percentage., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Achievement of greater than or equal to (>=) 10 percent (%) weight reduction, Measured as count of participants., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Achievement of >= 15 % weight reduction, Measured as count of participants., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Achievement of >= 20 % weight reduction, Measured as count of participants., From baseline (week 0) to end of treatment (week 68)|CagriSema (pooled doses) versus semaglutide (pooled doses): Continuous Glucose Monitoring (CGM) - Change in Time in Range (TIR) 3.9-10.0 millimoles per litre (mmol/L) (70-180 milligrams per decilitre [mg/dL]), Measured in percentage-points., From baseline (week -3) to end of treatment (week 68)|CagriSema versus semaglutide: CGM - Change in time in Tight Target Range (TITR) 3.9-7.8 (mmol/L) (70-140 mg/dL), Measured in percentage-points., From baseline (week -3) to end of treatment (week 68)|CagriSema versus semaglutide: Change in Systolic Blood Pressure (SBP), Measured in millimeters of mercury (mmHg)., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Ratio to baseline in triglycerides, Measured as ratio of triglycerides., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Ratio to baseline in non-High Density Lipoprotein (HDL) cholesterols, Measured as ratio of non-HDL cholesterol., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: CGM - Change in Time In Range (TIR) 3.9-10.0 mmol/L (70-180 mg/dL), Measured in percentage-points., From baseline (week -3) to end of treatment (week 68)|CagriSema versus semaglutide: Ratio to baseline in high sensitivity C-Reactive Protein (hsCRP), Measured as ratio of hsCRP., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Change in Fasting Plasma Glucose (FPG), Measured in mmol/L., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Achievement of HbA1c target values of less than (<) 7.0% (<53 millimoles per mole [mmol/mol]), Measured as count of participants., At end of treatment (week 68)|CagriSema versus semaglutide: Achievement of HbA1c target values of less than or equal to (≤)6.5% (≤48 mmol/mol), Measured as count of participants., At end of treatment (week 68)|CagriSema versus semaglutide: CGM - Change in time above range, >10.0 mmol/L (>180 mg/dL), Measured in percentage-points., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: CGM - Change in time above range, >13.9 mmol/L (>250 mg/dL), Measured in percentage-points., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: CGM - Within-day glycaemic variability (% coefficient of variation [CV]), Measured in percentage., At end of treatment (week 68)|CagriSema versus semaglutide: Achievement of ≥ 5 % weight reduction, Measured as count of participants., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Change in waist circumference, Measured in centimetre., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Change in Diastolic Blood Pressure (DBP), Measured in mmHg., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Ratio to baseline in total cholesterol, Measured as ratio of total cholesterol., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Ratio to baseline in HDL cholesterol, Measured as ratio of HDL cholesterol., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Ratio to baseline in low-density lipoprotein (LDL) cholesterol, Measured as ratio of LDL cholesterol., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Ratio to baseline in very low-density lipoprotein (VLDL) cholesterol, Measured as ratio of VLDL., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Ratio to baseline in free fatty acids, Measured as ratio of free fatty acids., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Change in Short Form (SF)-36v score- Physical component summary score, SF-36v2 measure consists of 36 items yielding 8 health domain scores and 2 component summary scores. SF-36v2 acute scores are norm-based scores, i.e. transformed to a scale where the 2009 US general population has a mean of 50 and an standard deviation of 10. Physical component summary score range from 6.1 to 79.7, with higher scores indicating better functional health and well-being., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Change in SF-36v2 score- Mental component summary score, SF-36v2 measure consists of 36 items yielding 8 health domain scores and 2 component summary scores. SF-36v2 acute scores are norm-based scores, i.e. transformed to a scale where the 2009 US general population has a mean of 50 and an standard deviation of 10. Mental component summary score range from -3.8 to 78.7, with higher scores indicating better functional health and well-being., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Change in Diabetes Treatment Satisfaction Questionnaire (DTSQ) score, DTSQc measures treatment satisfaction and diabetes-specific quality of life (QoL). The measure consists of 8 items yielding 1 global score and 2 single item scores. Total treatment satisfaction scores range from 0-36, with higher scores indicating greater satisfaction; the perceived frequency of hyperglycemia/hypoglycemia items are scored separately, with lower scores indicating better perceived blood glucose control., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide: Change in Treatment Related Impact Measure for Diabetes (TRIM-D) score, TRIM-D measures impact of diabetes treatment. The measure consists of 28 items yielding 5 domain scores and a total score. The scores were transformed to a 0-100 scale with higher scores indicating a better health state., From baseline (week 0) to end of treatment (week 68)|CagriSema versus semaglutide, placebo and cagrilintide: Number of treatment emergent adverse events (TEAEs), Measured as count of events., From baseline (week 0) to end of study (week 75)|CagriSema versus semaglutide: Number of clinically significant hypoglycaemic episodes (level 2) (<3.0 mmol/L (54 mg/dL), confirmed by BG meter), Measured as count of episodes., From baseline (week 0) to end of study (week 75)|CagriSema versus semaglutide: Number of severe hypoglycaemic episodes (level 3), Measured as count of episodes. Hypoglycaemia episodes (level 3) are the episodes associated with severe cognitive impairment requiring external assistance for recovery, with no specific glucose threshold., From baseline (week 0) to end of study (week 75)
Sponsor/Collaborators: Sponsor: Novo Nordisk A/S
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases: PHASE3
Enrollment: 2734
Study Type: INTERVENTIONAL
Study Designs: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Start Date: 2023-09-27
Completion Date: 2026-01-05
Results First Posted:
Last Update Posted: 2025-04-09
Locations: Univ of Alabama_Birmingham, Birmingham, Alabama, 35294, United States|Cahaba Research, Pelham, Alabama, 35124, United States|Velocity Clinical Research-Phoenix, Phoenix, Arizona, 85006, United States|Synexus Rsch /Cnt Phnx Med C, Phoenix, Arizona, 85020, United States|Arkansas Clinical Research, Little Rock, Arkansas, 72205, United States|Velocity Clinical Res-Banning, Banning, California, 92220, United States|Velocity Clin Res-Chula Vista, Chula Vista, California, 91911, United States|John Muir Physicians Network, Concord, California, 94520, United States|Headlands Research California, LLC, Escondido, California, 92025, United States|Velocity Clin Res Gardena, Gardena, California, 90247, United States|Velocity Clin Res San Diego, La Mesa, California, 91942, United States|Loma Linda Univ Hlth Cr Endo, Loma Linda, California, 92354, United States|Facey Medical Foundation, Mission Hills, California, 91345, United States|Desert Oasis Hlthcr Med Group, Palm Springs, California, 92262, United States|Velocity Clin Res- San Bern, San Bernardino, California, 92408, United States|Linda Vista Health Care Ctr, San Diego, California, 92111, United States|Velocity Clin Res Santa Ana, Santa Ana, California, 92704, United States|Premier Medical Center, Inc., Toluca Lake, California, 91602, United States|Velocity Clin Res - Panorama, Van Nuys, California, 91405, United States|Optumcare Colorado Springs, Colorado Springs, Colorado, 80906, United States|Northeast Research Institute, Jacksonville, Florida, 32204, United States|Clinical Trial Services Corp, Miami, Florida, 33144, United States|Bioclinical Research Alliance, Miami, Florida, 33155, United States|New Horizon Research Center, Miami, Florida, 33165, United States|South Broward Research LLC, Miramar, Florida, 33027, United States|West Orange Endocrinology, Ocoee, Florida, 34761, United States|Optimal Research Sites, Orange City, Florida, 32763, United States|AdventHealth Diab Inst, Orlando, Florida, 32804, United States|Hope Clin Res & Wellness, Conyers, Georgia, 30094, United States|East Coast Institute for Res, Macon, Georgia, 31210, United States|Endocrine Research Solutions, Inc., Roswell, Georgia, 30076, United States|Endocrine Research Solutions, Roswell, Georgia, 30076, United States|St. Luke's Health System, Boise, Idaho, 83702, United States|Solaris Clinical Research, Meridian, Idaho, 83646, United States|Cedar-Crosse Research Center, Chicago, Illinois, 60607, United States|Clinical Invest Special_Gurnee, Gurnee, Illinois, 60031, United States|Endeavor Health, Skokie, Illinois, 60077, United States|Evanston Premier Hlthcr Res, Skokie, Illinois, 60077, United States|Iowa Diabetes & Endo Res Ctr, West Des Moines, Iowa, 50266, United States|Alliance for Multispec Res, Newton, Kansas, 67114, United States|Cotton-O'Neil Diab & Endo Ctr, Topeka, Kansas, 66606, United States|Velocity Clin Res Lafayette, Lafayette, Louisiana, 70508, United States|BTC of New Bedford, LLC, New Bedford, Massachusetts, 02740, United States|Velocity Clin Res Gulfport, Gulfport, Mississippi, 39503, United States|Diabetes & Endo Specialists Inc, Chesterfield, Missouri, 63017, United States|Premier Research Inc., Trenton, New Jersey, 08611, United States|Velocity Clin Res Albuquerque, Albuquerque, New Mexico, 87107, United States|Albany Medical College - Endo, Albany, New York, 12203, United States|Velocity Clin Res Syracuse, East Syracuse, New York, 13057, United States|Southgate Medical Group, LLP, West Seneca, New York, 14224, United States|Great Lakes Medical Research, Westfield, New York, 14787, United States|University of North Carolina, Chapel Hill, North Carolina, 27514, United States|PharmQuest Life Sciences LLC, Greensboro, North Carolina, 27408, United States|Carteret Medical Group, Morehead City, North Carolina, 28557, United States|Piedmont Healthcare/Research, Statesville, North Carolina, 28625, United States|Accellacare, Wilmington, North Carolina, 28401, United States|Radiant Research Inc. - Akron, Akron, Ohio, 44311, United States|Aventiv Research, Dublin, Ohio, 43016, United States|Alliance for Multispec Res, Norman, Oklahoma, 73069, United States|Clinical Res Collaborative, Cumberland, Rhode Island, 02864, United States|Velocity Clin Res Providence, East Greenwich, Rhode Island, 02818, United States|AnMed Health IMA, Anderson, South Carolina, 29621, United States|Synexus Clin Res US-Anderson, Anderson, South Carolina, 29621, United States|Velocity Clinical Res-Anderson, Anderson, South Carolina, 29621, United States|Velocity Clin Res Gaffney, Gaffney, South Carolina, 29340, United States|Spartanburg Medical Research, Spartanburg, South Carolina, 29303, United States|Velocity Clin Res Spartanburg, Spartanburg, South Carolina, 29303, United States|Holston Medical Group Pc, Bristol, Tennessee, 37620-7352, United States|Holston Medical Group, Kingsport, Tennessee, 37660, United States|Clinical Research Associates, Nashville, Tennessee, 37203, United States|Arlington Family Res. Ctr Inc, Arlington, Texas, 76012-4637, United States|Velocity Clin Res Austin, Austin, Texas, 78759, United States|Velocity Clinical Res-Dallas, Dallas, Texas, 75230, United States|North Texas Endocrine Center, Dallas, Texas, 75231, United States|Synexus Clin Res Dallas, Dallas, Texas, 75234, United States|Cedar Health Research, Dallas, Texas, 75251, United States|Juno Research, LLC_Houston, Houston, Texas, 77040, United States|Synergy Groups Medical, Houston, Texas, 77061, United States|PlanIt Research, PLLC, Houston, Texas, 77079, United States|Medical Colleagues-Texas LLP, Katy, Texas, 77450, United States|Sante Clinical Research, Kerrville, Texas, 78028, United States|Discovery MMS Services, INC, Missouri City, Texas, 77459, United States|AES San Antonio, San Antonio, Texas, 78229, United States|Univ Of Texas Hlth Science Cntr, San Antonio, Texas, 78229, United States|NE Clin Res of San Antonio, San Antonio, Texas, 78233, United States|Consano Clinical Research, LLC, Shavano Park, Texas, 78231, United States|DM Clin Rsrch/Fam Diag Clinic, Tomball, Texas, 77375, United States|Diabetes & Endo Treatment Spec, Sandy, Utah, 84093, United States|Velocity Clin Res-Salt Lk City, West Jordan, Utah, 84088, United States|TPMG Clinical Research, Newport News, Virginia, 23606, United States|Rainier Clin Res Ctr Inc, Renton, Washington, 98057, United States|St. Vincent Hosp-Prevea Health, Green Bay, Wisconsin, 54303, United States|Mautalen Salud e investigación, Caba, Buenos Aires, C1128 AAF, Argentina|Sanatorio Güemes, Caba, City Of Buenos Aires, C1180AAX, Argentina|Instituto de Investigaciones Clínicas Rosario, Rosario, Santa Fe, S2000CUD, Argentina|STAT Research, Buenos Aires, C1023AAB, Argentina|Centro Medico Dra. Laura Maffei e Investigacion Clínica Apli, Buenos Aires, C1425AGC, Argentina|Centro de Investigación y Prevención Cardiovascular, Caba, C1061AAS., Argentina|Clinical Research Facility, Charles Perkins Centre, Camperdown, New South Wales, 2050, Australia|Momentum Clinical Research Darlinghurst, Darlinghurst, New South Wales, 2010, Australia|Macquarie University, Macquarie Park, New South Wales, 2109, Australia|Hunter Diabetes Centre, Merewether, New South Wales, 2291, Australia|Logan Hospital, Meadowbrook, Queensland, 4131, Australia|Southern Adelaide Diabetes & Endocrine Services, Oaklands Park, South Australia, 5046, Australia|St Vincent's Hospital - Melbourne, Fitzroy, Victoria, 3065, Australia|Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, 3004, Australia|Cline Research Center, Curitiba, Parana, 80030-480, Brazil|CPQuali Pesquisa Clínica Ltda, São Paulo, Sao Paulo, 01228-000, Brazil|CPCLIN - Centro de Pesquisas Clínicas, São Paulo, Sao Paulo, 01228-200, Brazil|"IPSMC - d-r Nikolay Kostadinov" EOOD, Burgas, 8000, Bulgaria|"Dr Tatyana Metalova - ambulatory for individual practice for specialised medical care for endocrinology" EOOD, Gotse Delchev, 2900, Bulgaria|Medical Center Zdrave Lom, Lom, 3600, Bulgaria|Medical centre Razgrad OOD, Razgrad, 7200, Bulgaria|Diagnostic Consulting Center Ascendent, Sofia, 1202, Bulgaria|"Medical Center Maraya Med" EOOD, Sofia, 1756, Bulgaria|Medical centre Clinic Nova, Varna, 9000, Bulgaria|UMHAT Sveta Marina EAD, Varna, 9010, Bulgaria|Centricity Research Calgary, Calgary, Alberta, T2H 2G4, Canada|Guilford Med Clinic, Surrey, British Columbia, V3R 4H6, Canada|TLC Diabetes and Endocrinology, Surrey, British Columbia, V3T 2V6, Canada|Ocean West Research Clinic, Surrey, British Columbia, V3Z 2N6, Canada|Hilltop Medical Clinic, Surrey, British Columbia, V4A 0C1, Canada|Spectrum Health Clinic, Vancouver, British Columbia, V6Z 2T1, Canada|G.A. Research Associates Ltd., Moncton, New Brunswick, E1G 1A7, Canada|Centricity Res. Barrie Endo, Barrie, Ontario, L4N 7L3, Canada|Centricity Research Brampton, Brampton, Ontario, L6S 0C6, Canada|Centricity Research Vaughn, Concord, Ontario, L4K 4M2, Canada|Medical Trust Clinics, Inc., Courtice, Ontario, L1E2J5, Canada|Centricity Research Etobicoke, Etobicoke, Ontario, M9R 4E1, Canada|Milestone Research, London, Ontario, N5W 6A2, Canada|Western Univ. Cnt for Studies in Fam Med, London, Ontario, N6G 2M1, Canada|Centricity Research Ottawa LMC, Ottawa, Ontario, K2J 0V2, Canada|Centricity Research Toronto, Toronto, Ontario, M4G 3E8, Canada|Diabetes Heart Research Centre, Toronto, Ontario, M6G 1M2, Canada|Centre Medical Acadie, Montreal, Quebec, H4N 2W2, Canada|Centricity Res Pointe-Claire, Pointe-Claire, Quebec, H9R 4S3, Canada|ALPHA Recherche Clinique, Quebec City, Quebec, G3K 2P8, Canada|Ctr de Med Metab de Lanaudiere, Terrebonne, Quebec, J6X 4P7, Canada|Diex Recherche Victoriaville, Victoriaville, Quebec, G6P 3Z8, Canada|Diex Recherche Quebec Inc., Quebec, G1V 4T3, Canada|Clin des Mal Lipid de Quebec, Quebec, G1V 4W2, Canada|Centre de Recherche Saint-Louis, Quebec, G1W 4R4, Canada|Beijing Friendship Hospital, Capital Medical University-Endocrinology, Beijing, Beijing, 100050, China|Chinese People's Liberation Army General Hospital-Endocrinology, Beijing, Beijing, 100853, China|Chongqing University Three Gorges Hospital, Chongqing, Chongqing, 404000, China|Huaihe Hospital of Henan University-Endocrinology, Kaifeng, Henan, 475000, China|The Second Affiliated Hospital of Nanjing Medical University-Endocrinology, Nanjing, Jiangsu, 210011, China|Suzhou Municipal Hospital-Endocrinology, Suzhou, Jiangsu, 215002, China|The Affiliated Hospital of Jiangsu University-Endocrinology, Zhenjiang, Jiangsu, 212001, China|Jinan Central Hospital, Ji'Nan, Shandong, 250000, China|Poliklinika Solmed, Zagreb, Grad Zagreb, 10000, Croatia|Poliklinika SLAVONIJA OSIJEK, Osijek, Osječko - Baranjska Županija, 31000, Croatia|KBC Rijeka, Endokrinologija, Rijeka, Primorsko - Goranska Županija, 51 000, Croatia|Thalassotherapia Opatija, Opatija, 51 410, Croatia|Opca bolnica Dr. Josip Bencevic, Slavonski Brod, 35 000, Croatia|Opca bolnica Varazdin, Varazdin, 42 000, Croatia|IKEM Centrum Diabetologie, Praha 4, Czech Republic, 140 21, Czechia|University Hospital U sv. Anny, Brno, 602 00, Czechia|Edumed Broumov, Broumov, 550 01, Czechia|Diahaza s.r.o., Holešov, 76901, Czechia|DIALINE s.r.o., Plzeň 3, 301 00, Czechia|Diabet2 s.r.o., Praha 1, 110 00, Czechia|MUDr. Michala Pelikanova, Praha 4, 140 00, Czechia|Aarhus Universitetshospital, Steno Diabetes Center Aarhus, Aarhus N, 8200, Denmark|Steno Diabetes Center Copenhagen, Herlev, 2730, Denmark|Hillerød Endokrinologisk amb. H0652, Hillerød, 3400, Denmark|Hvidovre Hospital Endokrinologisk forsk. afs. 159, Hvidovre, 2650, Denmark|Bispebjerg Hospital, IC-Forskning, København, 2400, Denmark|Steno Diabetes Center Odense, Odense C, 5000, Denmark|Terveystalo Jyväskylä, Jyväskylä, 40100, Finland|Seinäjoen keskussairaala, Seinäjoki, 60220, Finland|Pihlajalinna Koskiklinikka, Tampere, 33100, Finland|Terveystalo Tampere Rautatienkatu, Tampere, 33100, Finland|Turku University Hospital, Turku, 20520, Finland|Medizinisches Versorgungszentrum Am Bahnhof Spandau GbR, Berlin, 13597, Germany|Diabetologische Schwerpunktpraxis Daaden, Daaden, 57567, Germany|Diabeteszentrum-Do Dres. K U. Ch. Busch GbR, Dortmund, 44137, Germany|Uniklinik TU Dresden Med. Klinik III, Dresden, 01307, Germany|Zentrum fuer klinische Studien Suedbrandenburg GmbH, Elsterwerda, 04910, Germany|InnoDiab Forschung GmbH, Essen, 45136, Germany|MVZ Diabeteszentrum Dr. Tews GmbH, Gelnhausen, 63571, Germany|Diabetes-Zentrum-Wilhelmsburg GbR, Hamburg, 21109, Germany|Diabetes Zentrum Wandsbek Berufsausuebungsgemeinschaft GbR, Hamburg, 22041, Germany|Diabetologische Gemeinschaftspraxis Dr. Staudenmeyer und Dr. Schiwietz, Lingen, 49808, Germany|Die Praxis am Ludwigsplatz, Ludwigshafen, 67059, Germany|Universitätsklinikum Schleswig-Holstein - Medizinischen Klinik I am Campus Lübeck, Lübeck, 23538, Germany|Medicover Neuroendokrinologie MVZ, München, 81667, Germany|RED-Institut für medizinische Forschung und Fortbildung GmbH, Oldenburg in Holstein, 23758, Germany|University Hospital of Athens ATTIKON, Athens, Attica, 12462, Greece|General Hospital Of Thessaloniki Papageorgiou, Nea Efkarpia, Thessaloniki, 56429, Greece|Iatriko Psychicou Private Clinic, Athens, 115 25, Greece|"Laiko" General Hospital of Athens, Athens, 11527, Greece|General hospital of Athens 'G.Gennimatas', Athens, 11527, Greece|Iatriko Athinon (Athens Medical Canter), Athens, 15125, Greece|Univ Gen Hospital Larisa, Endocrinology & Metabolic Disease, Larissa, 41110, Greece|"AHEPA" University Hospital of Thessaloniki, Thessaloniki, 54621, Greece|"AHEPA" University Hospital of Thessaloniki, Thessaloniki, 54636, Greece|"Ippokrateio" G.H. of Thessaloniki, Thessaloniki, 54642, Greece|EUROMEDICA Gen Clinic The/ki, Endocrin,Metabolism,Diabetes, Thessaloniki, 54643, Greece|Szegedi Tudomanyegyetem St Györgyi Albert Klinikai Központ, Szeged, Csongrád-Csanád, 6725, Hungary|Debreceni Egyetem Belgyógyászati Klinika, Debrecen, Hajdu-Bihar, 4032, Hungary|Óbudai Egészségügyi Centrum, Budapest, 1036, Hungary|Bajcsy-Zsilinszky Kórház, Budapest, 1106, Hungary|MH Egészségügyi Központ, Budapest, 1134, Hungary|Kaposi Mór Oktató Kórház, Kaposvár, 7400, Hungary|Markusovszky Egyetemi Oktatókórház, Szombathely, 9700, Hungary|Yalamanchi Hospitals and Research centres pvt ltd, Vijaywada, Andhra Pradesh, 520002, India|Gauhati Medical College and Hospital, Guwahati, Assam, 781032, India|Lifecare Hospital and Research Centre, Bengaluru, Karnataka, 560066, India|K R Hospital, Mysuru, Karnataka, 570001, India|Ashirwad Hospital and Research Centre, Thane, Maharashtra, 421004, India|SMS Medical College & Hospital, Jaipur, Rajasthan, 302004, India|Madras Diabetes Research Foundation, Chennai, Tamil Nadu, 600086, India|Gleneagles Hospitals, Hyderabad, Telangana, 500004, India|Dr P V Rao - Diabetes Research Centre, Hyderabad, Telangana, 50082, India|Apollo Multispeciality Hospital, Kolkata, Kolkata, West Bengal, 700054, India|Swasthya Diabetes Care, Ahmedabad, 390013, India|Lady Hardinge Medical College, New Delhi, 110001, India|Linn clinic - Clalit Health Services, Haifa, 35152, Israel|Clalit sick fund Herzlia, Herzlia, 4630945, Israel|Diabetes Clinic Wolfson MC, Holon, 58100, Israel|Diabetes Unit Hadassah Ein Karem MC, Jerusalem, 91120, Israel|Kaplan MC, Rehovot, 76100, Israel|Endrocrinolgy Clinic - Sheba Medical Center, Tel Hashomer, 52621, Israel|AOU Careggi Firenze, Firenze, Fi, 50134, Italy|Istituto Scientifico San Raffaele, Milano, MI, 20132, Italy|AOU Careggi Firenze, Firenze, Toscana, 50134, Italy|Azienda Sanitaria Usl Toscana Sud Est - Ospedale San Donato, Arezzo, 52100, Italy|Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, 24127, Italy|Azienda Ospedaliero-Universitaria Renato Dulbecco, Catanzaro, 88100, Italy|Università degli studi G. D'Annunzio Chieti Pescara - CAST, Chieti Scalo, 66100, Italy|Azienda Ospedaliera Luigi Sacco, Milano, 20157, Italy|Azienda Ospedaliera Universitaria Federico II di Napoli, Napoli, 80131, Italy|AOUP Giaccone Palermo, Palermo, 90127, Italy|Dip. di Medicina Interna Policlinico Universitario Palermo, Palermo, 90127, Italy|Azienda Ospealiero Universitaria Policlinico Umberto I, Roma, 00161, Italy|Policlinico A. Gemelli, Rome, 00168, Italy|Seino Internal Medicine Clinic, Koriyama-shi, Fukushima, Japan, 963-8851, Japan|Abe Diabetes Clinic_Internal Medicine, Oita-shi, Oita, Japan, 870 0039, Japan|Akaicho Clinic, Chiba-shi, Chiba, 260-0804, Japan|Naka Kinen Clinic, Ibaraki, 311-0113, Japan|Minami Akatsuka Clinic, Mito-shi, Ibaraki, 311-4153, Japan|Medical Research Institute KITANO HOSPITAL, Diabetes & Endocrinology, Osaka-shi, Osaka, 530-8480, Japan|Tokyo-Eki Center-building Clinic, Tokyo, 103-0027, Japan|Fukuwa Clinic, Tokyo, 104-0031, Japan|The catholic university of Korea, Bucheon St.Mary's Hospital, Bucheon-si, Gyeonggi-do, 14647, Korea, Republic of|Yeungnam University Medical Center, Daegu, 42415, Korea, Republic of|Chosun University Hospital, Gwangju, 501-717, Korea, Republic of|Kyunghee University Medical Center, Seoul, 02447, Korea, Republic of|Korea University Anam Hospital, Seoul, 02841, Korea, Republic of|Seoul National University Hospital, Seoul, 03080, Korea, Republic of|Kangbuk Samsung Hospital, Seoul, 03181, Korea, Republic of|Centro de investigación en Artritis y Osteoporosis S.C., Mexicali, Baja California, 21200, Mexico|Centro de Investigacion Clinica Endocrinologica de Jalisco, Guadalajara, Jalisco, 44670, Mexico|Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika, Lodz, Lodzkie, 93-513, Poland|Specjalistyczny Gabinet Diabetologiczny Radoslaw Rumianowski, Gorzow Wielkopolski, Lubuskie, 66-400, Poland|Malopolskie Centrum Sercowo-Naczyniowe, Chrzanow, Malopolskie, 32-500, Poland|Instytut Diabetologii Sp. z o.o., Warszawa, Mazovian Voivodeship, 02-117, Poland|Centrum Medyczne Medyk Sp. z o.o., Rzeszow, Podkarpackie, 35-055, Poland|Osteo Medic s.c. Artur Racewicz Jerzy Supronik, Bialystok, Podlaskie, 15-351, Poland|NZOZ Specjalistyczny Osrodek Internistyczno-Diabetologiczny Małgorzata Arciszewska, Bialystok, Podlaskie, 15-435, Poland|PAKS III Oddział Kardiologii Inwazyjnej, Angiologii i Elektrokardiologii, Dąbrowa-Górnicza, Slaskie, 41-300, Poland|PAKS III Oddział Kardiologii Inwazyjnej, Angiologii i Elektrokardiologii, Tychy, Slaskie, 43-100, Poland|Velocity Nova Sp. z o.o., Lublin, 20-362, Poland|KO-MED Centra Kliniczne Sp. z o.o., Pulawy, 24-100, Poland|Velocity Nova Sp. z o.o., Staszow, 28-200, Poland|NBR Polska Tomasz Klodawski, Warszawa, 00-710, Poland|Panstwowy Instytut Medyczny Ministerstwa Spraw Wewnetrznych I Administracji, Warszawa, 02-507, Poland|Velocity Nova Sp. z o.o., Staszow, Świętokrzyskie, 28-200, Poland|Institutul National De Diabet Nutritie Si Boli Metabolice Prof.Dr.N.Paulescu Bucuresti- Ion Movila, Bucharest, Bucurestii, 020475, Romania|Spitalul Clinic Judetean Urgenta Cluj-Napoca, Cluj Napoca, Cluj, 400006, Romania|Diabmed Dr Popescu Alexandrina SRL, Ploiesti, Prahova, 100179, Romania|CMI Dr. Busegeanu Mihaela Magdalena, Ploiesti, Prahova, 100342, Romania|Cabinet Medical de Diabet, Nutritie si Boli Metabolice-Dr. Zaharie Daniela Gabriela, Zalau, Salaj, 450112, Romania|CMI Dr. Pletea Noemi SRL, Bacau, 600154, Romania|Mariodiab Clinic SRL, Brasov, 500101, Romania|Centrul Medical de Diagnostic si Tratament Ambulatoriu Neomed, Brasov, 500283, Romania|Diabet Med SRL, Bucuresti, 050913, Romania|Urodiamed SRL, Craiova, 200349, Romania|S.C Milena Sante SRL, Galati, 800001, Romania|Bella Praxis S.R.L., Pascani, 705200, Romania|Poli Cardinal Med Srl, Reghin, 545300, Romania|Clin. Centre Vojvodina, Clin. endocr., diab. and met. dis., Novi Sad, Vojvodina, 21000, Serbia|CHC Zvezdara, Clinical department for endocrinology, Belgrade, 11000, Serbia|Endocrinology, Diabetes and Metabolism Diseases Clinic, Belgrade, 11000, Serbia|Clinical Hospital Center Bezanijska Kosa, Belgrade, 11080, Serbia|Clinical Centre Kragujevac, Internal Diseases Clinic, Endocrinology department, Kragujevac, 34000, Serbia|Clinical Centre Kragujevac, Internal Diseases Clinic, Endocr, Kragujevac, 34000, Serbia|DIADA, s.r.o., Bardejov, 08501, Slovakia|Diabetologicka ambulancia DIOLI s.r.o., Kosice, 040 01, Slovakia|DIOLI s.r.o., Kosice, 040 01, Slovakia|MediVet s.r.o., Malacky, 90101, Slovakia|DIALIPID, s.r.o., Presov, 080 01, Slovakia|MUDr. Jan Culak, s.r.o., Prievidza, 971 01, Slovakia|DIACENTRUM, s.r.o., Ruzomberok, 034 01, Slovakia|MEDI-DIA s.r.o., Sabinov, 083 01, Slovakia|DEImedi, s. r. o., Surany, 942 01, Slovakia|ARETEUS s.r.o., Trebisov, 075 01, Slovakia|iDia s. r. o., Ziar nad Hronom, 965 01, Slovakia|Healthcare centre Kocevje, Kocevje, 1330, Slovenia|Healthcare Centre Koper, Koper, 6000, Slovenia|Dermatologija Bartenjev, Ljubljana, 1000, Slovenia|UKC Maribor - diabetes, Maribor, 2000, Slovenia|Healtcare Centre Nova Gorica, Nova Gorica, 5000, Slovenia|Hospital Topolšica, Topolšica, 3326, Slovenia|Phoenix Pharma, Port Elizabeth, Eastern Cape, 6001, South Africa|Newtown Clinical Research, Johannesburg, Gauteng, 2001, South Africa|Sandton Medical Research, Johannesburg, Gauteng, 2196, South Africa|Clinresco Centres (Pty) Ltd, Kempton Park, Gauteng, 1619, South Africa|Clinical Trial Systems (CTC), Pretoria, Gauteng, 0186, South Africa|Paarl Research Centre, Paarl, Western Cape, 7646, South Africa|Hospital Vall d'Hebron, Barcelona, 08035, Spain|Complejo Hospitalario Universitario A Coruña, La Coruña, 15006, Spain|ABS La Roca del Vallés, La Roca del Vallés, 08430, Spain|Hospital Universitario de Móstoles, Móstoles, 28935, Spain|Hospital General de Segovia, Segovia, 40002, Spain|Hospital Infanta Luisa, Sevilla, 41010, Spain|Hospital La Fe - Endocrinología y Nutrición, Valencia, 46026, Spain|Clemenstorgets Hjärtmottagning, Lund, 222 21, Sweden|Forskningsmottagning Internmedicin (tidigare KFE), Malmö, 205 02, Sweden|CTC GoCo Mölndal, Mölndal, 431 53, Sweden|Karolinska Universitetssjukhuset Solna,FOU Tema Hjärta Kärl, Stockholm, 171 64, Sweden|Överviktsenheten Örebro universitetssjukhus, Örebro, 701 85, Sweden|Changhua Christian Hospital, Changhua City, 500, Taiwan|Taipei Medical University Hospital, Taipei city, 110, Taiwan|Cukurova Universitesi Tip Fakultesi, Adana, 01790, Turkey|Akdeniz University Tip Fakultesi Hastanesi, Antalya, 07058, Turkey|Eskisehir Osmangazi University School of Medicine, Eskisehir, 26040, Turkey|Haseki Sultangazi, Istanbul, 34098, Turkey|Seyrantepe Hamidiye Etfal Egitim ve Arastirma Hastanesi, Istanbul, 34371, Turkey|Istanbul Universitesi Istanbul Tip Fakultesi - Endokrinoloji, Istanbul, 34390, Turkey|Basaksehir Cam ve Sakura Sehir Hastanesi, Istanbul, 34480, Turkey|T.C SB Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, 34722, Turkey|Recep Tayyip Erdoğan Üni. Eğitim ve Araştırma Hastanesi, Rize, 53020, Turkey|Tekirdag Namık Kemal UTF, Tekirdag, 59030, Turkey|Lister Hospital, Stevenage, Hertfordshire, SG1 4AB, United Kingdom|Aberdeen Royal Infirmary, Aberdeen, AB25 2ZP, United Kingdom|Oldfield Surgery, Bath, BA2 3HT, United Kingdom|Oakenhurst Surgery, Blackburn, BB2 1AX, United Kingdom|Ninewells Hospital, Dundee, DD1 9SY, United Kingdom|University Hospital Aintree, Liverpool, L9 7AL, United Kingdom|Norfolk and Norwich University Hospital Trust, Norwich, NR4 7UY, United Kingdom|Pickering Medical Practice, Pickering, YO18 8BL, United Kingdom|Moorgreen Hospital, Southampton, SO30 3JB, United Kingdom|Joint Clinical Research Facility - Swansea, Swansea, SA2 8PP, United Kingdom|Royal Cornwall Hospital (Treliske), Truro, TR1 3LJ, United Kingdom
URL: https://clinicaltrials.gov/show/NCT06065540

Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress