| Trial ID: | L0389 |
| Source ID: | NCT01284114
|
| Associated Drug: |
Aliskiren
|
| Title: |
Effects of Aliskiren in Elderly Hypertensive Chronic Kidney Disease (CKD) Patients
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT01284114/results
|
| Conditions: |
Hypertension|Chronic Kidney Disease
|
| Interventions: |
DRUG: Aliskiren
|
| Outcome Measures: |
Primary: The Change of Blood Pressure, The change of systolic blood pressure and diastolic blood pressure, baseline and 6 month|The Change of Heart Function Confirmed by Echocardiograph, Left ventricular ejection fraction (LVEF)were measured by echocardiogram at baseline and 6 month. Plasma BNP level were measured by the radioimmunoassay (RIA) method at baseline and 6month., baseline and 6 month|The Change of BNP, Plasma BNP level were measured by the radioimmunoassay (RIA) method at baseline and 6month., baseline and 6month|The Change of eGFR, eGFR was calculated at baseline and at 6 month using a modified version of the Modification of Diet in Renal Disease (MDRD) formula of the Japanese Society of Nephrology as follows: eGFR (ml/min/1.73 m2) = 194 × age-0.287 × serum creatinine-1.094 (multiplied by 0.739 for females)., baseline and 6 month|The Change of Urine Albumin/ Creatinine Ratio (UACR)., The UACR was measured at baseline, Week12 and Week24, baseline and 6 months | Secondary: The Change of Oxidative Stress Markers Confirmed by Plasma Level of 8-OHdG and d-ROM, 6 months
|
| Sponsor/Collaborators: |
Sponsor: Jichi Medical University
|
| Gender: |
ALL
|
| Age: |
OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
23
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2011-02
|
| Completion Date: |
2012-05
|
| Results First Posted: |
2012-10-22
|
| Last Update Posted: |
2012-10-22
|
| Locations: |
Niimi city Yukawa National health insurance clinic, Niimi, Okayama, 719-2643, Japan|Konan Hospital, Oyama, Tochigi, 329-0214, Japan|Kurosu Hospital, Sakura, Tochigi, 329-1395, Japan|Jichi Medical University, Shimotsuke, Tochigi, 3290498, Japan
|
| URL: |
https://clinicaltrials.gov/show/NCT01284114
|
