| Trial ID: | L3958 |
| Source ID: | NCT00527995
|
| Associated Drug: |
Sildenafil
|
| Title: |
Acute Effects of Sildenafil on Endothelial Function in People With Diabetes
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes Mellitus|Endothelial Dysfunction
|
| Interventions: |
DRUG: Sildenafil
|
| Outcome Measures: |
Primary: Improvement of flow mediated dilatation of the brachial artery following a single dose of 100mg Sildenafil., 60 minutes | Secondary: Change in hemodynamics and cardiovascular parasympathetic and sympathetic nerve function using time domain and frequency domain indexes of heart rate variability (HRV) and baroreflex sensitivity (BRS) following a single dose of 100mg Sildenafil., 60 minutes
|
| Sponsor/Collaborators: |
Sponsor: Ruhr University of Bochum
|
| Gender: |
MALE
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE3
|
| Enrollment: |
40
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2001-08
|
| Completion Date: |
2003-06
|
| Results First Posted: |
|
| Last Update Posted: |
2007-09-11
|
| Locations: |
German Diabetes Center, Duesseldorf, North Rhine-Westphalia, 40225, Germany
|
| URL: |
https://clinicaltrials.gov/show/NCT00527995
|
