| Trial ID: | L3993 |
| Source ID: | NCT01741181
|
| Associated Drug: |
Vitamin D Supplementation
|
| Title: |
Vitamin D Supplementation in Patients With Diabetes Mellitus Type 2
|
| Acronym: |
DIMENSION
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes Mellitus Type 2|Vitamin D Deficiency
|
| Interventions: |
DRUG: Vitamin D supplementation|DRUG: Placebo Pill
|
| Outcome Measures: |
Primary: Endothelial function as assessed by the reactive hyperemia index and endothelial progenitor cells, Endothelial function will be tested by using the EndoPAT machine which measures the reactive hyperemia index and by estimating the no. of endothelial progenitor cells in the peripheral blood by flow cytometry., 16 weeks | Secondary: Markers of endothelial cell activation and thrombogenesis, Biomarkers measured include hsCRP, e-selectin,von-willebrand factor(vWF), 16 weeks|No. of circulating endothelial cells and endothelial microparticles, The no. of circulating endothelial cells and endothelial microparticles will be estimated before and after intervention., 16-20 weeks
|
| Sponsor/Collaborators: |
Sponsor: Tan Tock Seng Hospital | Collaborators: Duke-NUS Graduate Medical School|National Healthcare Group, Singapore
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
64
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
|
| Start Date: |
2012-09
|
| Completion Date: |
2014-11
|
| Results First Posted: |
|
| Last Update Posted: |
2014-11-18
|
| Locations: |
Tan Tock Seng Hospital, Singapore, 308433, Singapore
|
| URL: |
https://clinicaltrials.gov/show/NCT01741181
|
