| Trial ID: | L4217 |
| Source ID: | NCT01238224
|
| Associated Drug: |
Tadalafil
|
| Title: |
Effects of PDE-5 Inhibition on Postprandial Hyperglycemia in Type 2 Diabetes
|
| Acronym: |
|
| Status: |
TERMINATED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes
|
| Interventions: |
DRUG: Tadalafil
|
| Outcome Measures: |
Primary: Capillary recruitment, muscle glucose uptake and circulating glucose levels following a meal, Capillary recruitment and glucose uptake in forearm muscle as well as circulating glucose levels following acute administration of tadalafil or placebo in type 2 diabetes patients., Five hours after a mixed meal | Secondary: Vascular function and circulating biomarkers., Arterial stiffness as measured by pulse wave velocity and circulating concentrations of metabolic variables, Five hours after a mixed meal
|
| Sponsor/Collaborators: |
Sponsor: Vastra Gotaland Region
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE1
|
| Enrollment: |
22
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2009-11
|
| Completion Date: |
2011-11
|
| Results First Posted: |
|
| Last Update Posted: |
2020-02-12
|
| Locations: |
The Wallenberg Laboratory, Dept of Molecular and Clinical Medicine, Sahlgrenska University Hospital, Bruna stråket 16,, Göteborg, SE 413 45, Sweden
|
| URL: |
https://clinicaltrials.gov/show/NCT01238224
|
