| Trial ID: | L0430 |
| Source ID: | NCT04919564
|
| Associated Drug: |
Furosemide In 0.9 % Nacl 100 Mg/100 Ml (1 Mg/Ml)
|
| Title: |
Low Dose Continuous Furosemide Effect on Cardiac Surgery Patients With Kidney Dysfunction
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT04919564/results
|
| Conditions: |
Chronic Kidney Disease|Cardiac Disease
|
| Interventions: |
DRUG: Furosemide in 0.9 % NaCl 100 Mg/100 mL (1 mg/mL)|DRUG: NaCl 0.9%
|
| Outcome Measures: |
Primary: Glomerular Filtration Rate at Baseline, Glomerular Filtration Rate measured at baseline, baseline / before induction to anesthesia|Glomerular Filtration Rate at 12 Hours From Drug Infusion, Glomerular Filtration Rate measured at 12 hours from the initiation of drug infusion, 12 hours from drug infusion|Glomerular Filtration Rate at 24 Hours From Drug Infusion, Glomerular Filtration Rate measured at 24 hours from the initiation of drug infusion, 24 hours after from infusion|Glomerular Filtration Rate at 48 Hours From Drug Infusion, Glomerular Filtration Rate measured at 48 hours from the initiation of drug infusion, 48 hours from drug infusion|Glomerular Filtration Rate at 120 Hours From Drug Infusion, Glomerular Filtration Rate measured at 120 hours from the initiation of drug infusion, 120 hours from drug infusion|Therapeutic Dose of Continuous Diuretic Infusion, number of participants with Therapeutic Dose of Continuous Diuretic Infusion, 28 days (or until hospital discharge)|Renal Replacement Therapy, number of participant with Renal Replacement Therapy, 28 days (or until hospital discharge) | Secondary: ICU Length of Stay, The length of stay in ICU, 28 days (or until hospital discharge)|In Hospital Mortality, number of In Hospital mortality, 28 days (or until hospital discharge)
|
| Sponsor/Collaborators: |
Sponsor: National Cardiovascular Center Harapan Kita Hospital Indonesia
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE2
|
| Enrollment: |
90
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
|
| Start Date: |
2021-05-27
|
| Completion Date: |
2022-02-28
|
| Results First Posted: |
2024-01-05
|
| Last Update Posted: |
2024-01-05
|
| Locations: |
National Cardiovascular Center Harapan Kita Jakarta, Jakarta, 11420, Indonesia
|
| URL: |
https://clinicaltrials.gov/show/NCT04919564
|
