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Clinical Trial Details

Trial ID: L4413
Source ID: NCT00747149
Associated Drug: Rosuvastatin
Title: A Diabetes Study to Treat A Population Previously Not at Target
Acronym: ADAPT
Status: COMPLETED
Study Results: YES
Results: https://ClinicalTrials.gov/show/NCT00747149/results
Conditions: Type 2 Diabetes
Interventions: DRUG: Rosuvastatin
Outcome Measures: Primary: Percentage of Subjects Achieving Canadian Low Density Lipoprotein Cholesterol (LDL-C) Target Goals (i.e. LDL-C ≤ 2.0 mmol/L) After 12 Weeks of Rosuvastatin Therapy, The number of subjects achieving Canadian Low density lipoprotein cholesterol (LDL-C) target goals (i.e. LDL-C ≤ 2.0 mmol/L) over the total number subjects treated after 12 weeks of rosuvastatin therapy multiplied by 100, 12 Weeks | Secondary: Percentage of Subjects Achieving Total Cholesterol (TC)/ High-density Lipoprotein Cholesterol (HDLC) Ratio (i.e. TC/HDL < 4.0 mmol/L) at 6 and 12 Weeks of Treatment, Proportion of subjects achieving total cholesterol (TC)/ High-density lipoprotein cholesterol (HDLC) ratio (i.e. TC/HDL \< 4.0 mmol/L) at 6 and 12 weeks of treatment, 6 and 12 Weeks|Mean Percent Change in Total Cholesterol (TC), Low Density Lipoprotein Cholesterol (LDL-C), High-density Lipoprotein Cholesterol (HDLC) , TC/HDL-C Ratio, Non-HDL-C, Triglycerides and Apolipoprotein B (ApoB) /Apolipoprotein A1 (ApoA-1) Ratio, 6 and 12 Weeks|Mean High Sensitivity C-reactive Protein (hsCRP) Value at Week 6 and 12, 6 and 12 Weeks|Incidence of Adverse Events and Abnormal Laboratory Values After 12 Weeks of Therapy, 6 and 12 Weeks
Sponsor/Collaborators: Sponsor: AstraZeneca
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases: PHASE4
Enrollment: 598
Study Type: INTERVENTIONAL
Study Designs: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Start Date: 2008-05
Completion Date: 2009-08
Results First Posted: 2011-07-04
Last Update Posted: 2011-08-31
Locations: Research Site, Calgary, Alberta, Canada|Research Site, Edmonton, Alberta, Canada|Research Site, Red Deer, Alberta, Canada|Research Site, Spruce Grove, Alberta, Canada|Research Site, St Albert, Alberta, Canada|Research Site, Chilliwack, British Columbia, Canada|Research Site, Coquitlam, British Columbia, Canada|Research Site, Delta, British Columbia, Canada|Research Site, Kelowna, British Columbia, Canada|Research Site, Maple Ridge, British Columbia, Canada|Research Site, Penticton, British Columbia, Canada|Research Site, Victoria, British Columbia, Canada|Research Site, Portage La Prairie, Manitoba, Canada|Research Site, Winnipeg, Manitoba, Canada|Research Site, Bathurst, New Brunswick, Canada|Research Site, Woodstock, New Brunswick, Canada|Research Site, Carbonear, Newfoundland and Labrador, Canada|Research Site, Mount Pearl, Newfoundland and Labrador, Canada|Research Site, St John's, Newfoundland and Labrador, Canada|Research Site, Halifax, Nova Scotia, Canada|Research Site, Kentville, Nova Scotia, Canada|Research Site, Pubnico, Nova Scotia, Canada|Research Site, Sydney Mines, Nova Scotia, Canada|Research Site, Truro, Nova Scotia, Canada|Research Site, Aylmer, Ontario, Canada|Research Site, Bolton, Ontario, Canada|Research Site, Chatham, Ontario, Canada|Research Site, Fort Erie, Ontario, Canada|Research Site, Georgetown, Ontario, Canada|Research Site, Hamilton, Ontario, Canada|Research Site, Kingston, Ontario, Canada|Research Site, Kitchener, Ontario, Canada|Research Site, London, Ontario, Canada|Research Site, Mississauga, Ontario, Canada|Research Site, Morrisburg, Ontario, Canada|Research Site, Nepean, Ontario, Canada|Research Site, Newmarket, Ontario, Canada|Research Site, North York, Ontario, Canada|Research Site, Oshawa, Ontario, Canada|Research Site, Ottawa, Ontario, Canada|Research Site, Scaborough, Ontario, Canada|Research Site, Scarborough, Ontario, Canada|Research Site, Smith Falls, Ontario, Canada|Research Site, St Catherines, Ontario, Canada|Research Site, St. Catharines, Ontario, Canada|Research Site, Sudbury, Ontario, Canada|Research Site, Thornhill, Ontario, Canada|Research Site, Thorold, Ontario, Canada|Research Site, Thunder Bay, Ontario, Canada|Research Site, Toronto, Ontario, Canada|Research Site, Welland, Ontario, Canada|Research Site, Willowdale, Ontario, Canada|Research Site, Windsor, Ontario, Canada|Research Site, Woodstock, Ontario, Canada|Research Site, Charlottetown, Prince Edward Island, Canada|Research Site, Kensington, Prince Edward Island, Canada|Research Site, Montague, Prince Edward Island, Canada|Research Site, Anjou, Quebec, Canada|Research Site, Dolbeau-mistassini, Quebec, Canada|Research Site, Drummondville, Quebec, Canada|Research Site, Forestville, Quebec, Canada|Research Site, Gatineau, Quebec, Canada|Research Site, Joliette, Quebec, Canada|Research Site, L'ile- Perrot, Quebec, Canada|Research Site, La Sarre, Quebec, Canada|Research Site, Laval, Quebec, Canada|Research Site, Longueuil, Quebec, Canada|Research Site, Montreal, Quebec, Canada|Research Site, Roberval, Quebec, Canada|Research Site, Roxton Pond, Quebec, Canada|Research Site, Saint-bruno-lac-saint-jean, Quebec, Canada|Research Site, Saint-charles-borromee, Quebec, Canada|Research Site, Saint-leonard, Quebec, Canada|Research Site, Saint-marc-des-carrieres, Quebec, Canada|Research Site, Saint-pie, Quebec, Canada|Research Site, Sainte Gedeon-de-beauce, Quebec, Canada|Research Site, Sherbrooke, Quebec, Canada|Research Site, Thetford Mines, Quebec, Canada|Research Site, Trois-rivieres, Quebec, Canada|Research Site, Moose Jaw, Saskatchewan, Canada|Research Site, Porcupine Plain, Saskatchewan, Canada|Research Site, Saskatoon, Saskatchewan, Canada|Research Site, Yorkton, Saskatchewan, Canada|Research Site, Quebec, Canada
URL: https://clinicaltrials.gov/show/NCT00747149

Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress