| Trial ID: | L4459 |
| Source ID: | NCT01122641
|
| Associated Drug: |
Vildagliptin
|
| Title: |
The Vascular Effects of Vildagliptin in Insulin Resistant Individuals
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Insulin Resistance|Microvascular Disease
|
| Interventions: |
DRUG: Vildagliptin|DRUG: Placebo
|
| Outcome Measures: |
Primary: Capillary pressure, Capillary pressure will be reduced in those treated with DPP-4 inhibitor, 3 months | Secondary: Macular thickness, Measured by optical coherence tomography, 3 months
|
| Sponsor/Collaborators: |
Sponsor: Royal Devon and Exeter NHS Foundation Trust | Collaborators: National Institute for Health Research, United Kingdom|Novartis Pharmaceuticals
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE3
|
| Enrollment: |
15
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
|
| Start Date: |
2010-05
|
| Completion Date: |
2014-08-01
|
| Results First Posted: |
|
| Last Update Posted: |
2017-04-25
|
| Locations: |
Diabetes and Vascular Research Department, Exeter, Devon, EX2 5AX, United Kingdom
|
| URL: |
https://clinicaltrials.gov/show/NCT01122641
|
