| Trial ID: | L4533 |
| Source ID: | NCT00461136
|
| Associated Drug: |
Aliskiren
|
| Title: |
Time Course of the Antiproteinuric and Blood Pressure Lowering Effects After Initiation of Renin Inhibition With Aliskiren in Type 2 Diabetes
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes Type 2
|
| Interventions: |
DRUG: Aliskiren
|
| Outcome Measures: |
Primary: To evaluate the time-course of the antiproteinuric effect of renin inhibition with Aliskiren in patients with Type 2 diabetes suffering from incipient and/or established nephropathy. | Secondary: To measure blood pressure changes over time during the onset and offset of effect.|To investigate whether there is a change on biomarkers of inflammation and cardiovascular risk.
|
| Sponsor/Collaborators: |
Sponsor: Novartis
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE1|PHASE2
|
| Enrollment: |
18
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2005-08
|
| Completion Date: |
2006-11
|
| Results First Posted: |
|
| Last Update Posted: |
2016-09-23
|
| Locations: |
Novartis, Gentofte, 2820, Denmark
|
| URL: |
https://clinicaltrials.gov/show/NCT00461136
|
