| Outcome Measures: |
Primary: Growth hormone area under the curve., Treatment effect (placebo vs lixisenatide) on growth hormone area under curve (AUC) is compared between patients with type 1 diabetes and healthy volunteers., 0-150 minutes after study drug administration | Secondary: Growth hormone peak, Maximum growth hormone concentration measured after study drug administration., 30, 60, 90, 120, and 150 minutes after the study drug administration.|Glucose nadir, Lowest glucose concentration measured after the study drug administration, 30, 60, 90, 120, and 150 minutes after the study drug administration|C-peptide peak, Maximum c-peptide concentration measured after the study drug administration, 30, 60, 90, 120, and 150 minutes after the study drug administration|Cortisol peak, Maximum cortisol concentration measured after the study drug administration, 30, 60, 90, 120, and 150 minutes after the study drug administration|Adrenocorticotropic hormone (ACTH) peak, Maximum ACTH concentration measured after the study drug administration, 30, 60, 90, 120, and 150 minutes after the study drug administration|Prolactin peak, Maximum prolactin concentration measured after the study drug administration, 30, 60, 90, 120, and 150 minutes after the study drug administration|Copeptin peak, Maximum copeptin concentration measured after the study drug administration, 30, 60, 90, 120, and 150 minutes after the study drug administration|Aldosterone peak, Maximum aldosterone concentration measured after the study drug administration, 30, 60, 90, 120, and 150 minutes after the study drug administration | Other: Nausea, The intensity of nausea on a 0-10 points visual analog scale, where 0 indicates no nausea and 10 worst imaginable nausea., 30, 60, 90, 120, and 150 minutes after the study drug administration|Systolic and diastolic blood pressure, The change in systolic and diastolic blood pressure compared to baseline., 30, 60, 90, 120, and 150 minutes after the study drug administration|Heart rate, The change in heart rate compared to baseline., 30, 60, 90, 120, and 150 minutes after the study drug administration.
|
