| Trial ID: | L0460 |
| Source ID: | NCT01541267
|
| Associated Drug: |
Aliskiren, Eplerenon, Telmisartan
|
| Title: |
The Effect of Various Types of the Renin-angiotensin-aldosterone System Blockade on Proteinuria
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Chronic Kidney Disease|Proteinuria
|
| Interventions: |
DRUG: aliskiren, eplerenon, telmisartan
|
| Outcome Measures: |
Primary: Difference in urinary albumin-to-creatinine ratio (UACR) between treatment arms, changes of UACR, baseline and the end of 8 week treatments | Secondary: Difference in transforming growth factor beta (TGF-beta) between treatment arms, Changes of urinary excretion of transforming growth factor beta (TGF-beta), baseline and the end of 8 week treatments|Difference in serum potassium and creatinine between treatment arms, baseline and the end of 8 week treatments
|
| Sponsor/Collaborators: |
Sponsor: Medical University of Gdansk
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
20
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2009-12
|
| Completion Date: |
2011-11
|
| Results First Posted: |
|
| Last Update Posted: |
2012-02-29
|
| Locations: |
|
| URL: |
https://clinicaltrials.gov/show/NCT01541267
|
