| Trial ID: | L4635 |
| Source ID: | NCT00738023
|
| Associated Drug: |
Rosiglitazone
|
| Title: |
Free Fatty Acid-Induced Hypertension in Obese Subjects With Type 2 Diabetes
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT00738023/results
|
| Conditions: |
Type 2 Diabetes|Hypertension
|
| Interventions: |
DRUG: Rosiglitazone|DRUG: Normal saline 0.9%|DRUG: Intralipid 20%
|
| Outcome Measures: |
Primary: Changes in Systolic Blood Pressure During Initial Intralipid Infusion, Systolic blood pressure change from baseline during an 48-hour intralipid infusion, Baseline, 48 hours | Secondary: Changes in Systolic Blood Pressure During Saline Infusions, Systolic blood pressure change from baseline during an 48-hour normal saline infusion in obese diabetic subjects, 48 hours|Changes in Systolic Blood Pressure During Intralipid Infusion Post-rosiglitazone Intervention, Systolic blood pressure change from baseline during an 48-hour intralipid infusion after taking rosiglitazone for 6 weeks in obese diabetic subjects, 48 hours
|
| Sponsor/Collaborators: |
Sponsor: Emory University | Collaborators: GlaxoSmithKline
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
36
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2004-03
|
| Completion Date: |
2009-12
|
| Results First Posted: |
2014-12-30
|
| Last Update Posted: |
2014-12-30
|
| Locations: |
Grady Memorial Hospital, Atlanta, Georgia, 30303, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT00738023
|
