| Trial ID: | L4642 |
| Source ID: | NCT00699023
|
| Associated Drug: |
Ezetimibe Tablets
|
| Title: |
Ezetimibe and Statins on Postprandial Lipemia in Type 2 Diabetes
|
| Acronym: |
EZE
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Postprandial Lipemia|Type 2 Diabetes
|
| Interventions: |
DRUG: ezetimibe tablets|DRUG: simvastatin tablets|DRUG: placebo
|
| Outcome Measures: |
Primary: Incremental AUC after a fat-rich meal of cholesterol concentration in chylomicron and VLDL fractions, 6 weeks | Secondary: Incremental AUC after a fat rich-meal of apo B48 concentration- marker of the number of intestinally derived lipoproteins- in chylomicron and VLDL, 6 weeks|Fasting LDL concentration, 6 weeks|Cholesterol/triglyceride ratio in postprandial chylomicrons and VLDL fractions., 6 weeks|Postprandial LDL size, 6 weeks|Concentration and Composition of different lipoprotein subclasses in the fasting condition., 6 weeks
|
| Sponsor/Collaborators: |
Sponsor: Federico II University
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
13
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2008-06
|
| Completion Date: |
2009-10
|
| Results First Posted: |
|
| Last Update Posted: |
2009-11-04
|
| Locations: |
Department of Clinical and Experimental Medicine, Federico II University Hospital,, Naples, 80131, Italy
|
| URL: |
https://clinicaltrials.gov/show/NCT00699023
|
