| Trial ID: | L4656 |
| Source ID: | NCT04907708
|
| Associated Drug: |
Metformin
|
| Title: |
Comparative Effects of Metformin and Insulin on Stereological Studies and Immunohistochemistry of Placenta
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes Mellitus Arising in Pregnancy, Insulin-Requiring|Diabetes Mellitus in Pregnancy
|
| Interventions: |
DRUG: Metformin|DRUG: Insulin
|
| Outcome Measures: |
Primary: Mean morphometric diffusion capacity for oxygen (MMDC) in placental tissues, With detailed stereological assessment MMDC can be calculated for the placenta to visualize which group placenta allows better diffusion of oxygen, 15 months | Secondary: Percentage of immuno-antigens present in placental tissue, The percentage of immuno-antigens on the placental tissue is related to the hypoxic and vascular changes in the placenta., 15 months
|
| Sponsor/Collaborators: |
Sponsor: University of Karachi
|
| Gender: |
FEMALE
|
| Age: |
ADULT
|
| Phases: |
|
| Enrollment: |
156
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
|
| Start Date: |
2018-01-01
|
| Completion Date: |
2019-08-07
|
| Results First Posted: |
|
| Last Update Posted: |
2021-06-01
|
| Locations: |
Jinnah Post Graduate Medical Centre, Karachi, Sindh, 75510, Pakistan
|
| URL: |
https://clinicaltrials.gov/show/NCT04907708
|
