| Trial ID: | L4741 |
| Source ID: | NCT03980990
|
| Associated Drug: |
Metformin
|
| Title: |
Metformin Continuation Versus Interruption Following Coronary Angiography: a Pilot Randomized Controlled Trial
|
| Acronym: |
|
| Status: |
UNKNOWN
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Acute Coronary Syndrome|Unstable Angina|Diabetes Mellitus|Metformin Adverse Reaction
|
| Interventions: |
DRUG: Metformin
|
| Outcome Measures: |
Primary: Lactic Acidosis, Lactate Level \>5 mmol/L and HCO3\<18, 48-72 hours (or 72 hours for patients with staged PCI procedures within 48 hours of randomization) | Secondary: Acute Kidney Injury, Rise in baseline creatinine \>/= 25% or 27 umol/L, 48-72 hours (or 72 hours for patients with staged PCI procedures within 48 hours of randomization)|All cause mortality at hospital discharge, Death in hospital, Duration of hospital admission
|
| Sponsor/Collaborators: |
Sponsor: University of Saskatchewan
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
500
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2019-06-17
|
| Completion Date: |
2020-06-17
|
| Results First Posted: |
|
| Last Update Posted: |
2019-06-20
|
| Locations: |
Royal University Hospital, Saskatoon, Saskatchewan, S7N0W8, Canada
|
| URL: |
https://clinicaltrials.gov/show/NCT03980990
|
