| Trial ID: | L4777 |
| Source ID: | NCT00437008
|
| Associated Drug: |
Benfotiamine 1050mg, 3 Days
|
| Title: |
Effects of Benfotiamine and AGE on Endothelial Function in People With Diabetes
|
| Acronym: |
AGE-Benfo
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Endothelial Dysfunction|Type 2 Diabetes Mellitus
|
| Interventions: |
DRUG: Benfotiamine 1050mg, 3 days|BEHAVIORAL: high-AGE vs. low-AGE meal
|
| Outcome Measures: |
Primary: A high-AGE meal causes a more pronounced postprandial endothelial dysfunction comparing to a low-AGE meal in people with type 2 diabetes mellitus. | Secondary: The influence of high-AGE vs. low-AGE meal on the laboratory parameters that mirror AGE-metabolism, oxidative stress, endothelial dysfunction and inflammation shall be investigated.|To investigate whether treatment with Benfotiamine 1050mg/day for 3 days has a protective effect on endothelial function after a high-AGE meal
|
| Sponsor/Collaborators: |
Sponsor: Ruhr University of Bochum
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
21
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: PREVENTION
|
| Start Date: |
2004-11
|
| Completion Date: |
2006-01
|
| Results First Posted: |
|
| Last Update Posted: |
2007-02-19
|
| Locations: |
Heart and Diabetes Center NRW, Bad Oeynhausen, 32545, Germany
|
| URL: |
https://clinicaltrials.gov/show/NCT00437008
|
