| Trial ID: | L4926 |
| Source ID: | NCT02386943
|
| Associated Drug: |
Sitagliptin
|
| Title: |
Study on Exploring the Effect of DPP-4 Inhibitors on β-cell Function by Using the Two-step Hyperglycemic Clamp
|
| Acronym: |
|
| Status: |
UNKNOWN
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes
|
| Interventions: |
DRUG: Sitagliptin|DRUG: Saxagliptin|DRUG: Blank control
|
| Outcome Measures: |
Primary: β-cell function (measurement of insulin and c-peptide during the clamp study), The primary endpoints are the effects of DPP-4 inhibitors on β-cell function, with the measurement of insulin and c-peptide during the clamp study., 15 months | Secondary: α-cell function (measurement of glucagon during the clamp study), The secondary endpoints are the effects of DPP-4 inhibitors on α-cell function, with the measurement of glucagon during the clamp study., 15 months|Incretin effect (measurement of active GLP-1 during the clamp study), The secondary endpoints are the effects of DPP-4 inhibitors on incretin effect, with the measurement of active GLP-1 during the clamp study., 15 months
|
| Sponsor/Collaborators: |
Sponsor: Shanghai Jiao Tong University School of Medicine
|
| Gender: |
ALL
|
| Age: |
ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
12
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2013-12
|
| Completion Date: |
2015-03
|
| Results First Posted: |
|
| Last Update Posted: |
2015-03-12
|
| Locations: |
Shanghai Jiao Tong University School of Medicine, Shanghai, China
|
| URL: |
https://clinicaltrials.gov/show/NCT02386943
|
