| Trial ID: | L4969 |
| Source ID: | NCT02481479
|
| Associated Drug: |
Saxagliptin
|
| Title: |
Saxagliptin and Cardiac Structure and Function
|
| Acronym: |
SCARF
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes Mellitus, Non-Insulin-Dependent|Heart Failure
|
| Interventions: |
DRUG: Saxagliptin|DRUG: Saxagliptin|DRUG: saxagliptin
|
| Outcome Measures: |
Primary: The change in LVEF from baseline to 6 months, assess LVEF at baseline and at 6 months following treatment. CMR based LVEF assessment using Cvi 42., baseline, 6 months | Secondary: The change in E/e' from baseline to 6 months, Echocardiography assessed E and E', to determine ratio, and assess change from baseline to 6 months., baseline, 6 months|change in class indicators of signs and symptoms of heart failure at each visit, assess NYHA class at baseline and at 6 months, baseline, 6 months|Change in log-scale in NT-pro BNP, assess NT-ProBNP at baseline and at 6 months, baseline, 6 months
|
| Sponsor/Collaborators: |
Sponsor: Unity Health Toronto
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
18
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2015-06
|
| Completion Date: |
2018-08
|
| Results First Posted: |
|
| Last Update Posted: |
2020-03-30
|
| Locations: |
St Michael's Hospital, Toronto, Ontario, M5B1W8, Canada
|
| URL: |
https://clinicaltrials.gov/show/NCT02481479
|
