| Trial ID: | L4990 |
| Source ID: | NCT01155284
|
| Associated Drug: |
Sitagliptin And Lansoprazole
|
| Title: |
Combination Therapy With Sitagliptin and Lansoprazole to Restore Pancreatic Beta Cell Function in Recent-Onset Type 1 Diabetes
|
| Acronym: |
REPAIR-T1D
|
| Status: |
COMPLETED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT01155284/results
|
| Conditions: |
Type 1 Diabetes
|
| Interventions: |
DRUG: Sitagliptin and Lansoprazole|DRUG: Placebo
|
| Outcome Measures: |
Primary: 2 Hour C-peptide AUC in Response to MMTT, Blood samples for C-peptide were collected at baseline (pre-meal) and 15, 30, 60, 90 and 120 minutes post-meal., Month 12 | Secondary: 2 Hour C-peptide AUC in Response to MMTT, Blood samples for C-peptide were collected at baseline (pre-meal) and 15, 30, 60, 90, and 120 minutes post-meal., Month 6
|
| Sponsor/Collaborators: |
Sponsor: Sanford Health | Collaborators: Juvenile Diabetes Research Foundation
|
| Gender: |
ALL
|
| Age: |
CHILD, ADULT
|
| Phases: |
PHASE2
|
| Enrollment: |
70
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2010-08
|
| Completion Date: |
2015-03
|
| Results First Posted: |
2017-09-18
|
| Last Update Posted: |
2017-09-18
|
| Locations: |
Rady Children's Hospital, San Diego, California, 92123-4282, United States|Children's - St. Paul, Saint Paul, Minnesota, 55102, United States|Sanford Research/USD, Sioux Falls, South Dakota, 57104, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT01155284
|
