| Trial ID: | L0005 |
| Source ID: | NCT02190318
|
| Associated Drug: |
Losartan
|
| Title: |
Residual Renal Function Preservation in Peritoneal Dialysis Patients
|
| Acronym: |
|
| Status: |
UNKNOWN
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Chronic Renal Disease
|
| Interventions: |
DRUG: Losartan|DRUG: spirolactone|OTHER: blank control
|
| Outcome Measures: |
Primary: residual renal function of peritoneal dialysis patients, From date of randomization until the date of dropping out of the study or death from any cause, whichever came first, assessed up to 12 months. | Secondary: peritoneal membrane function, peritoneal membrane function is measured by peritoneal equilibration test to test the type of peritoneal transport. Briefly, a standard 4-hour dwell period was used (first exchange of the day), using a 2.5% glucose concentration 2-L volume exchange. The patient used their usual overnight dialysis regimen, and both the overnight and test drainage volumes were measured.The dialysate:plasma ratio of creatinine at the completion of the 4-hour dwell period (D/Pcreat) was used as the estimate of low-molecular-weight solute transport., From date of randomization until the date of dropping out of the study or death from any cause, whichever came first, assessed up to 12 months.
|
| Sponsor/Collaborators: |
Sponsor: Second Xiangya Hospital of Central South University | Collaborators: Baxter Healthcare Corporation
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
|
| Enrollment: |
96
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2013-11
|
| Completion Date: |
2015-12
|
| Results First Posted: |
|
| Last Update Posted: |
2014-08-01
|
| Locations: |
Changsha, Hunan, 410000, China
|
| URL: |
https://clinicaltrials.gov/show/NCT02190318
|
