| Trial ID: | L5158 |
| Source ID: | NCT03017703
|
| Associated Drug: |
Eplerenone
|
| Title: |
The Role of Aldosterone in Circulatory Disorders Within Type 2 Diabetes
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Endothelial Dysfunction|Insulin Resistance
|
| Interventions: |
DRUG: Eplerenone
|
| Outcome Measures: |
Primary: Vascular function, Femoral arterial blood flow in response to femoral arterially infused ACh, 8 weeks|Insulin sensitivity measured by a insulin clamp, Glucose infusion rate during euglycaemic-hyperinsulinaemic clamp, 8 weeks | Secondary: Vascular function, Microperfusion performed on blood vessels in vitro obtained from muscle biopsies, 8 weeks
|
| Sponsor/Collaborators: |
Sponsor: University of Southern Denmark
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
|
| Enrollment: |
27
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2016-12-01
|
| Completion Date: |
2019-12-15
|
| Results First Posted: |
|
| Last Update Posted: |
2021-06-02
|
| Locations: |
Cardiovascular and Renal Research, Odense, 5000, Denmark
|
| URL: |
https://clinicaltrials.gov/show/NCT03017703
|
