| Trial ID: | L0052 |
| Source ID: | NCT03170336
|
| Associated Drug: |
Amiloride
|
| Title: |
A New Application of Amiloride in the Treatment of Patient With Chronic Kidney Disease In Reducing Urinary PROtein
|
| Acronym: |
ANTI-UPRO
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Chronic Kidney Diseases
|
| Interventions: |
DRUG: Amiloride|DRUG: Hydrochlorothiazide
|
| Outcome Measures: |
Primary: The remission of proteinuria, after treatment for 12 weeks | Secondary: estimated Glomerular Filtration Rate, time to a 50% reduction in baseline estimated Glomerular filtration rate (according to CKD-EPI) and to doubling of baseline creatinine, after treatment for 12 weeks|creatinine, time to doubling of baseline creatinine, after treatment for 12 weeks|hyperkalemia, The ratio of hyperkalemia occurred at 12 weeks after treatment., at 12 weeks after treatment
|
| Sponsor/Collaborators: |
Sponsor: Guangdong Provincial People's Hospital
|
| Gender: |
ALL
|
| Age: |
CHILD, ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
40
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2018-03-01
|
| Completion Date: |
2020-08-01
|
| Results First Posted: |
|
| Last Update Posted: |
2020-09-18
|
| Locations: |
Nephrology Dept,Guangdong General Hospital, Guangzhou, Guangdong, China
|
| URL: |
https://clinicaltrials.gov/show/NCT03170336
|
